Corynebacterium urealyticum DSM 7109

Gram-positiveRodNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Bacteria from the genus Corynebacterium are Gram-positive, nonmotile rods. C.urealyticum is a strictly aerobic, lipid-requiring, urealytic bacterium of the human skin flora that causes urinary tract infections; strain DSM 7109 was recovered from a patient with alkaline-encrusted cystitis. Metabolic analysis of the lipid-requiring phenotype revealed the absence of a fatty acid synthase gene and the presence of a beta-oxidation pathway along with a large repertoire of auxillary genes for the degradation of exogenous fatty acids. A urease locus may play a pivotal role in virulence of C. urealyticum by the alkalinization of human urine and the formation of struvite stones. Multidrug resistance in DSM 7109 is mediated by transposable elements, conferring resistances to macrolides, lincosamides, ketolides, aminoglycosides, chloramphenicol, and tetracycline (modified from PubMed 18367281). (EBI Integr8)

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium urealyticum
StrainDSM 7109

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Corynebacterium urealyticum DSM 7109
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Corynebacterium urealyticum DSM 7109, complete sequence.

Gene Summary

Adenine Count

428363 bp

Thymine Count

420167 bp

Guanine Count

757668 bp

Cytosine Count

763021 bp

Genome Length

2369219 bp

Protein-coding Genes

1990 genes

Non-Coding Genes

77 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cation-translocating p-type atpaseCU_RS06625Not AvailableNegative1552439 - 155478181092.3
mbl fold metallo-hydrolaseCU_RS06630Not AvailableNegative1555046 - 155572924495.6
s-(hydroxymethyl)mycothiol dehydrogenaseCU_RS06635Not AvailableNegative1555799 - 155689938788.2
hypothetical proteinCU_RS06640Not AvailablePositive1557194 - 155752312207.5
dna primaseCU_RS06645Not AvailableNegative1557636 - 155964874281.4
fad-dependent oxidoreductaseCU_RS06650Not AvailablePositive1559803 - 156153062860.2
ribonuclease domain-containing proteinCU_RS06655Not AvailablePositive1561560 - 156206317483.7
deoxyguanosinetriphosphate triphosphohydrolaseCU_RS06660Not AvailableNegative1562077 - 156335746504.0
fmn-binding glutamate synthase family proteinCU_RS06665Not AvailableNegative1563454 - 156505558169.9
hypothetical proteinCU_RS06670Not AvailableNegative1565088 - 156562719930.4

Displaying genes 1361 – 1370 of 2067 in total

Metabolites

66 records
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Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002305(S)-2-ethyl-2-hydroxy-3-oxobutanoateC6H9O4Chemical structure of (S)-2-ethyl-2-hydroxy-3-oxobutanoateNot available
Average145.135Da
Monoisotopic145.0506324Da
BASm0002307(2R,3R)-2,3-dihydroxy-3-methylpentanoateC6H11O4Chemical structure of (2R,3R)-2,3-dihydroxy-3-methylpentanoateNot available
Average147.1491Da
Monoisotopic147.06573384Da
BASm00024581D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranosideC14H25NO11Chemical structure of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranosideNot available
Average383.35Da
Monoisotopic383.142760629Da
BASm0002751(S)-4-amino-5-oxopentanoateC5H9NO3Chemical structure of (S)-4-amino-5-oxopentanoateNot available
Average131.1299Da
Monoisotopic131.0582432Da
BASm0002826(2R)-3-phospho-glyceroyl phosphateC3H4O10P2Chemical structure of (2R)-3-phospho-glyceroyl phosphateNot available
Average262.005Da
Monoisotopic261.9301646Da
BASm0002833FMNH2C17H21N4O9PChemical structure of FMNH25666-16-0
Average456.3438Da
Monoisotopic456.1046148Da
BASm0002858all-trans-undecaprenyl phosphateC55H89O4PChemical structure of all-trans-undecaprenyl phosphateNot available
Average845.288Da
Monoisotopic844.6509455Da
BASm0002909O-acetyl-L-homoserineC6H11NO4Chemical structure of O-acetyl-L-homoserine7540-67-2
Average161.1558Da
Monoisotopic161.0688078Da

Displaying 1–10 of 66 metabolites

Health Effects

No health effects information available for this bacterium.