Megamonas rupellensis

Non-motileAnaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Negativicutes

Order

Selenomonadales

Family

Selenomonadaceae

Genus

Megamonas

Description

Megamonas rupellensis is a Gram-negative, rod-shaped microbe that thrives in mesophilic temperatures, categorized as a Chemoheterotroph, and can be found in various body sites, including the gastrointestinal tract, respiratory tract, and skin, across different species. As an Obligate Anaerobe, M. rupellensis requires the absence of oxygen to survive and grow. The Gram-negative characteristic indicates that the microbe's cell wall is composed of a thin peptidoglycan layer, which is typically associated with a higher degree of pathogenicity. The rod-shaped morphology allows for efficient movement and colonization in its environment. As a Chemoheterotroph, M. rupellensis relies on organic compounds for energy and carbon, breaking down complex molecules to sustain its metabolic processes. Its presence in various body sites highlights its adaptability and ability to coexist with other microorganisms. The mesophilic temperature preference suggests that M. rupellensis is well-suited to thrive in moderate temperatures, typical of many environmental and host ecosystems. The obligate anaerobic nature of M. rupellensis underscores its sensitivity to oxygen, which can be toxic to the microbe. M. rupellensis plays a significant role in the fermentation of complex carbohydrates, producing short-chain fatty acids that contribute to the health and balance of the host's microbiome, and its unique characteristics have led to its identification as a key player in the degradation of certain pollutants in anaerobic environments.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassNegativicutes
OrderSelenomonadales
FamilySelenomonadaceae
GenusMegamonas
SpeciesMegamonas rupellensis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens, Athletes
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Megamonas rupellensis strain AF27-12 AF27-12.Scaf67, whole genome

Gene Summary

Adenine Count

848588 bp

Thymine Count

835807 bp

Guanine Count

389664 bp

Cytosine Count

376803 bp

Genome Length

2451587 bp

Protein-coding Genes

2242 genes

Non-Coding Genes

146 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pucr family transcriptional regulatorDWY77_04700Not AvailableNegative959110 - 96030046276.2
cytosine deaminaseDWY77_04705Not AvailableNegative960418 - 96167447186.7
cytosine permeaseDWY77_04710Not AvailableNegative961707 - 96297845832.9
hypothetical proteinDWY77_04715Not AvailablePositive963606 - 9638188384.25
crispr-associated endoribonuclease cas6DWY77_04720Not AvailablePositive963894 - 96458627447.7
hypothetical proteinDWY77_04725Not AvailablePositive964614 - 96644972464.1
crispr-associated proteinDWY77_04730Not AvailablePositive966488 - 96754639642.6
type i-b crispr-associated protein cas5DWY77_04735Not AvailablePositive967547 - 96836531938.2
crispr-associated helicase cas3'DWY77_04740Not AvailablePositive968433 - 971102105368.0
dna2/cas4 domain-containing proteinDWY77_04745Not AvailablePositive971122 - 97161319077.5

Displaying genes 971 – 980 of 2388 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

8 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014039L-Lactic acidC3H6O3Chemical structure of L-Lactic acid79-33-4
Average90.0779Da
Monoisotopic90.031694058Da
BASm0014045Propionic acidC3H6O2Chemical structure of Propionic acid79-09-4
Average74.0785Da
Monoisotopic74.036779436Da
BASm0014079FuranC4H4OChemical structure of Furan110-00-9
Average68.074Da
Monoisotopic68.02621475Da
BASm0039640Streptococcus constellatusNot available7296-56-2Not available

Displaying 1–8 of 8 metabolites

Health Effects

Health ConditionRelationReference
NafldCausesPMC9767906

Displaying health effects 1 – 1 of 1 in total