Megamonas rupellensis

Non-motileAnaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Negativicutes

Order

Selenomonadales

Family

Selenomonadaceae

Genus

Megamonas

Description

Megamonas rupellensis is a Gram-negative, rod-shaped microbe that thrives in mesophilic temperatures, categorized as a Chemoheterotroph, and can be found in various body sites, including the gastrointestinal tract, respiratory tract, and skin, across different species. As an Obligate Anaerobe, M. rupellensis requires the absence of oxygen to survive and grow. The Gram-negative characteristic indicates that the microbe's cell wall is composed of a thin peptidoglycan layer, which is typically associated with a higher degree of pathogenicity. The rod-shaped morphology allows for efficient movement and colonization in its environment. As a Chemoheterotroph, M. rupellensis relies on organic compounds for energy and carbon, breaking down complex molecules to sustain its metabolic processes. Its presence in various body sites highlights its adaptability and ability to coexist with other microorganisms. The mesophilic temperature preference suggests that M. rupellensis is well-suited to thrive in moderate temperatures, typical of many environmental and host ecosystems. The obligate anaerobic nature of M. rupellensis underscores its sensitivity to oxygen, which can be toxic to the microbe. M. rupellensis plays a significant role in the fermentation of complex carbohydrates, producing short-chain fatty acids that contribute to the health and balance of the host's microbiome, and its unique characteristics have led to its identification as a key player in the degradation of certain pollutants in anaerobic environments.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassNegativicutes
OrderSelenomonadales
FamilySelenomonadaceae
GenusMegamonas
SpeciesMegamonas rupellensis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens, Athletes
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Megamonas rupellensis strain AF27-12 AF27-12.Scaf67, whole genome

Gene Summary

Adenine Count

848588 bp

Thymine Count

835807 bp

Guanine Count

389664 bp

Cytosine Count

376803 bp

Genome Length

2451587 bp

Protein-coding Genes

2242 genes

Non-Coding Genes

146 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
trna dihydrouridine synthase dusbDWY77_08820Not AvailableNegative1807095 - 180805135851.6
type iii pantothenate kinaseDWY77_08825Not AvailableNegative1808048 - 180886629999.8
biotin--[acetyl-coa-carboxylase] ligaseDWY77_08830Not AvailableNegative1808887 - 180986736492.4
asch domain-containing proteinDWY77_08835Not AvailablePositive1810126 - 181047313544.5
Trna-glyNot AvailableNot AvailablePositive1810656 - 1810730Not Available
Trna-cysNot AvailableNot AvailablePositive1810734 - 1810808Not Available
dutp diphosphataseDWY77_08850Not AvailablePositive1810913 - 181136216625.7
replication-associated recombination protein aDWY77_08855Not AvailablePositive1811436 - 181272248514.5
trna 2-thiouridine(34) synthase mnmaDWY77_08860Not AvailablePositive1812829 - 181389639054.2
ferrous iron transport protein aDWY77_08865Not AvailablePositive1814101 - 18143258004.15

Displaying genes 1781 – 1790 of 2388 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

8 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000503L-rhamnoseC6H12O5Chemical structure of L-rhamnose3615-41-6
Average164.1565Da
Monoisotopic164.0684735Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014039L-Lactic acidC3H6O3Chemical structure of L-Lactic acid79-33-4
Average90.0779Da
Monoisotopic90.031694058Da
BASm0014045Propionic acidC3H6O2Chemical structure of Propionic acid79-09-4
Average74.0785Da
Monoisotopic74.036779436Da
BASm0014079FuranC4H4OChemical structure of Furan110-00-9
Average68.074Da
Monoisotopic68.02621475Da
BASm0039640Streptococcus constellatusNot available7296-56-2Not available

Displaying 1–8 of 8 metabolites

Health Effects

Health ConditionRelationReference
NafldCausesPMC9767906

Displaying health effects 1 – 1 of 1 in total