Phenylobacterium zucineum HLK1

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Alphaproteobacteria

Order

Caulobacterales

Family

Caulobacteraceae

Genus

Phenylobacterium

Description

The genus Phenylobacterium comprises 5 species, the first 4 of which were isolated from water or soil. Strain HLK1 was isolated from the human erythroleukemia cell line K562. It is a Gram-negative rod, motile with a polar flagellum that is strictly aerobic and nonfermentative. Its grows optimally at 37 degrees C between pH 6.5 and 7.5. It is a facultative intracellular organism and may have pathogenic relevance with humans and mammals, as it can infect at least HeLa cells. Unlike known intracellular pathogens, P. zucineum maintains a stable association with its host cell without apparently affecting the growth and morphology of the latter (modified from PubMed 16908113 and 18700039). (EBI Integr8)

Taxonomy

Kingdom	Pseudomonadati
Phylum	Pseudomonadota
Class	Alphaproteobacteria
Order	Caulobacterales
Family	Caulobacteraceae
Genus	Phenylobacterium
Species	Phenylobacterium zucineum
Strain	HLK1

Profile

Physiology
Gram staining properties	Negative
Shape	Rod
Mobility	Yes
Flagellar presence	Yes
Number of membranes	2

AI-generated image based on bacteria physiology

Ecology, Host, and Life Cycle
Oxygen requirements	Aerobe
Optimal temperature	37
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Not Available
Cell arrangement	Not Available
Sporulation	Not Available
Energy source	Not Available
Pathogenicity	Not Available

Genome Summary

Phenylobacterium zucineum HLK1 plasmid unnamed, complete sequence.

NC_011143.1 NC_011144.1

Gene Summary

Adenine Count

60195 bp

Thymine Count

60273 bp

Guanine Count

132226 bp

Cytosine Count

130282 bp

Genome Length

382976 bp

Protein-coding Genes

386 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
acyl-coa carboxylase subunit beta	PHZ_RS14150	Not Available	Positive	2940623 - 2942182	56655.7
nad(p)h-dependent flavin oxidoreductase	PHZ_RS14155	Not Available	Negative	2942196 - 2943203	35883.3
fadr/gntr family transcriptional regulator	PHZ_RS14160	Not Available	Positive	2943384 - 2944100	25844.2
mfs transporter	PHZ_RS14165	Not Available	Negative	2944141 - 2945529	49320.3
enoyl-coa hydratase/isomerase family protein	PHZ_RS14170	Not Available	Negative	2945588 - 2946367	27553.0
dha2 family efflux mfs transporter permease subunit	PHZ_RS14175	Not Available	Positive	2946467 - 2948077	56547.7
hypothetical protein	PHZ_RS14180	Not Available	Negative	2948120 - 2948809	25219.4
acyclic terpene utilization atua family protein	PHZ_RS14185	Not Available	Negative	2948980 - 2950821	65403.1
Trna-met	Not Available	Not Available	Positive	2950934 - 2951009	Not Available
simpl domain-containing protein	PHZ_RS14195	Not Available	Positive	2951109 - 2951855	26098.3

Displaying genes 3251 – 3260 of 4346 in total

Pathways

719 pathways

2,3-Dihydroxybenzoate Biosynthesis

Biosynthesis of Siderophore Group Nonribosomal Peptides

Palmitate Biosynthesis

Show All 719 Pathways

Metabolite ID	Metabolite name	CAS number	Average mass Monoisotopic mass
BASm0000237	(R)-4'-phosphopantothenateC9H18NO8P	Not available	Average299.2149Da Monoisotopic299.0770031Da
BASm0000250	2,5-didehydro-D-gluconateC6H7O7	`53736-12-2`	Average191.1156Da Monoisotopic191.019177578Da
BASm0000251	2-dehydropantoateC6H9O4	Not available	Average145.1333Da Monoisotopic145.050083776Da
BASm0000253	2-oxopent-4-enoateC5H5O3	Not available	Average113.093Da Monoisotopic113.024417601Da
BASm0000260	3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5	Not available	Average405.556Da Monoisotopic405.264647871Da
BASm0000274	aldehydo-D-galacturonateC6H9O7	Not available	Average193.132Da Monoisotopic193.0353762Da
BASm0000387	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6	Not available	Average455.432Da Monoisotopic455.1564286Da
BASm0000428	3-oxoadipateC6H6O5	Not available	Average158.11Da Monoisotopic158.022620453Da
BASm0000516	6-deoxyerythronolide BC21H38O6	Not available	Average386.5228Da Monoisotopic386.2668389Da
BASm0000553	biphenyl-2,3-diolC12H10O2	Not available	Average186.2066Da Monoisotopic186.0680796Da

Displaying 1–10 of 837 metabolites

Health Effects

No health effects information available for this bacterium.