Phenylobacterium zucineum HLK1

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Alphaproteobacteria

Order

Caulobacterales

Family

Caulobacteraceae

Genus

Phenylobacterium

Description

The genus Phenylobacterium comprises 5 species, the first 4 of which were isolated from water or soil. Strain HLK1 was isolated from the human erythroleukemia cell line K562. It is a Gram-negative rod, motile with a polar flagellum that is strictly aerobic and nonfermentative. Its grows optimally at 37 degrees C between pH 6.5 and 7.5. It is a facultative intracellular organism and may have pathogenic relevance with humans and mammals, as it can infect at least HeLa cells. Unlike known intracellular pathogens, P. zucineum maintains a stable association with its host cell without apparently affecting the growth and morphology of the latter (modified from PubMed 16908113 and 18700039). (EBI Integr8)

Taxonomy

Kingdom	Pseudomonadati
Phylum	Pseudomonadota
Class	Alphaproteobacteria
Order	Caulobacterales
Family	Caulobacteraceae
Genus	Phenylobacterium
Species	Phenylobacterium zucineum
Strain	HLK1

Profile

Physiology
Gram staining properties	Negative
Shape	Rod
Mobility	Yes
Flagellar presence	Yes
Number of membranes	2

AI-generated image based on bacteria physiology

Ecology, Host, and Life Cycle
Oxygen requirements	Aerobe
Optimal temperature	37
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Not Available
Cell arrangement	Not Available
Sporulation	Not Available
Energy source	Not Available
Pathogenicity	Not Available

Genome Summary

Phenylobacterium zucineum HLK1 plasmid unnamed, complete sequence.

NC_011143.1 NC_011144.1

Gene Summary

Adenine Count

60195 bp

Thymine Count

60273 bp

Guanine Count

132226 bp

Cytosine Count

130282 bp

Genome Length

382976 bp

Protein-coding Genes

386 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	PHZ_RS23605	Not Available	Positive	2361035 - 2363089	76685.0
gsu2403 family nucleotidyltransferase fold protein	PHZ_RS11560	Not Available	Positive	2363260 - 2364252	35131.3
hypothetical protein	PHZ_RS22730	Not Available	Positive	2364249 - 2364539	10545.4
tetr/acrr family transcriptional regulator	PHZ_RS11565	Not Available	Positive	2364937 - 2365614	25251.3
mfs transporter	PHZ_RS11570	Not Available	Negative	2365611 - 2366774	38430.5
class ii aldolase/adducin family protein	PHZ_RS11575	Not Available	Negative	2366771 - 2367421	22794.6
carbohydrate kinase family protein	PHZ_RS11580	Not Available	Negative	2367418 - 2368365	31626.3
aminotransferase class iii-fold pyridoxal phosphate-dependent enzyme	PHZ_RS11585	Not Available	Positive	2368450 - 2369727	46686.7
n,n-dimethylformamidase beta subunit family domain-containing protein	PHZ_RS11590	Not Available	Negative	2369776 - 2371326	56161.9
tonb-dependent receptor	PHZ_RS11595	Not Available	Positive	2371550 - 2373781	80439.4

Displaying genes 2721 – 2730 of 4346 in total

Pathways

719 pathways

2,3-Dihydroxybenzoate Biosynthesis

Biosynthesis of Siderophore Group Nonribosomal Peptides

Palmitate Biosynthesis

Show All 719 Pathways

Metabolite ID	Metabolite name	CAS number	Average mass Monoisotopic mass
BASm0000237	(R)-4'-phosphopantothenateC9H18NO8P	Not available	Average299.2149Da Monoisotopic299.0770031Da
BASm0000250	2,5-didehydro-D-gluconateC6H7O7	`53736-12-2`	Average191.1156Da Monoisotopic191.019177578Da
BASm0000251	2-dehydropantoateC6H9O4	Not available	Average145.1333Da Monoisotopic145.050083776Da
BASm0000253	2-oxopent-4-enoateC5H5O3	Not available	Average113.093Da Monoisotopic113.024417601Da
BASm0000260	3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5	Not available	Average405.556Da Monoisotopic405.264647871Da
BASm0000274	aldehydo-D-galacturonateC6H9O7	Not available	Average193.132Da Monoisotopic193.0353762Da
BASm0000387	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6	Not available	Average455.432Da Monoisotopic455.1564286Da
BASm0000428	3-oxoadipateC6H6O5	Not available	Average158.11Da Monoisotopic158.022620453Da
BASm0000516	6-deoxyerythronolide BC21H38O6	Not available	Average386.5228Da Monoisotopic386.2668389Da
BASm0000553	biphenyl-2,3-diolC12H10O2	Not available	Average186.2066Da Monoisotopic186.0680796Da

Displaying 1–10 of 837 metabolites

Health Effects

No health effects information available for this bacterium.