Borrelia duttonii Ly

Gram-negativeSpirillaNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Spirochaetota

Class

Spirochaetia

Order

Spirochaetales

Family

Borreliaceae

Genus

Borrelia

Description

Relapsing fever (RF) is a disease caused by several spirochetes of the genus Borrelia. Relapsing fever borrelioses are characterized by recurrent febrile episodes and spirochetemia. There are 2 forms; louse-borne relapsing fever (also known as urban or epidemic RF) is caused by Borrelia recurrentis, and is transmitted by the body louse Pediculus humanus humanus. It currently known in Ethiopia. Endemic tick-borne relapsing fever (TBRF) is a zoonotic disease transmitted worldwide by softbody ticks of the genus Ornithodoros. It is caused by at least 15 distinct Borrelia species throughout the world.Borrelia duttonii is endemic in Western Africa, where it causes TBRF, causing up to 6 relapses, no mortality but often adverse perinatal outcomes. Strain Ly was isolated from a 2-year-old girl with TBRF in Tanzania, and has 16 plasmids. Interestingly B.recurrentis strain A1 (BORRA), a causative agent of louse-borne relapsing fever RF, and sequenced by the same group at the same time, has been deduced to be a reduced form of B.duttonii undergoing genome decay. (HAMAP: BORDL)

Taxonomy

KingdomPseudomonadati
PhylumSpirochaetota
ClassSpirochaetia
OrderSpirochaetales
FamilyBorreliaceae
GenusBorrelia
SpeciesBorrelia duttonii
StrainLy

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Borrelia duttonii Ly
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangePsychrophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityYes

Genome Summary

Borrelia duttonii Ly plasmid pl70, complete sequence.

Gene Summary

Adenine Count

24282 bp

Thymine Count

22051 bp

Guanine Count

10664 bp

Cytosine Count

9410 bp

Genome Length

66407 bp

Protein-coding Genes

75 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

14

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
periplasmic-type flagellar collar protein flbbBDU_RS01440Not AvailableNegative310607 - 31122124395.7
hypothetical proteinBDU_RS01445Not AvailableNegative311214 - 31164517113.1
flii/yscn family atpaseBDU_RS01450Not AvailableNegative311642 - 31294948003.9
flagellar assembly protein flihBDU_RS01455Not AvailableNegative312966 - 31388635190.3
flagellar motor switch protein fligBDU_RS01460Not AvailableNegative313901 - 31493538954.1
flagellar basal-body ms-ring/collar protein flifBDU_RS01465Not AvailableNegative314951 - 31665765296.5
flagellar hook-basal body complex protein flieBDU_RS01470Not AvailableNegative316671 - 31700012428.9
flagellar basal body rod protein flgcBDU_RS01475Not AvailableNegative317016 - 31747416657.8
flagellar basal body rod protein flgbBDU_RS01480Not AvailableNegative317501 - 31790815501.6
hslu--hslv peptidase atpase subunitBDU_RS01485Not AvailableNegative317941 - 31929351619.8

Displaying genes 871 – 880 of 1448 in total

Metabolites

60 records
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Mass search
Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0002593(2E)-dodecenoyl-CoAC33H52N7O17P3SChemical structure of (2E)-dodecenoyl-CoA1066-12-2
Average943.789Da
Monoisotopic943.2353235Da
BASm0002963meso-2,6-diaminoheptanedioateC7H14N2O4Chemical structure of meso-2,6-diaminoheptanedioate922-54-3
Average190.1971Da
Monoisotopic190.0953569Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014038Malic acidC4H6O5Chemical structure of Malic acid97-67-6
Average134.0874Da
Monoisotopic134.021523302Da
BASm0014065N-AcetylmannosamineC8H15NO6Chemical structure of N-Acetylmannosamine7772-94-3
Average221.2078Da
Monoisotopic221.089937217Da
BASm0014096Cyclic AMPC10H12N5O6PChemical structure of Cyclic AMPNULL
Average329.2059Da
Monoisotopic329.052519653Da
BASm0014194Dodecanoic acidC12H24O2Chemical structure of Dodecanoic acidNULL
Average200.3178Da
Monoisotopic200.177630012Da
BASm0017265Uridine diphosphate-N-acetylglucosamineC17H27N3O17P2Chemical structure of Uridine diphosphate-N-acetylglucosamine528-04-1
Average607.3537Da
Monoisotopic607.081569477Da

Displaying 1–10 of 60 metabolites

Health Effects

No health effects information available for this bacterium.