Dorea formicigenerans ATCC 27755

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Dorea

Description

Dorea formicigenerans ATCC 27755 is a microorganism that thrives in environments with moderate temperatures, categorized as mesophilic, with an optimal growth temperature range of 25-40°C. This microbe is a chemoheterotroph, utilizing organic compounds as energy sources and reducing their complexity through cellular respiration. The energy production pathway employed by Dorea formicigenerans is fermentative, where glucose is converted into lactic acid and ATP is generated. The bacterium stains gram-positive, characterized by a thick peptidoglycan layer in its cell wall. Its cellular morphology is ovoid or coccoid in shape, with a diameter ranging from 0.5 to 1.5 μm. Dorea formicigenerans has been isolated from various human body sites, including the oral cavity, respiratory tract, and gastrointestinal tract, as well as from environmental samples. This widespread distribution suggests that the microbe is well adapted to colonize diverse habitats. As an obligate anaerobe, Dorea formicigenerans is unable to grow in the presence of oxygen and requires a low-oxygen or oxygen-free environment for survival. This adaptation is likely an evolutionary response to the microbe's inability to cope with oxidative stress. In addition to its scientific significance, Dorea formicigenerans ATCC 27755 has practical applications in the field of biotechnology. For instance, its ability to produce lactic acid from glucose makes it a potential candidate for industrial-scale fermented food production. Furthermore, the microbe's anaerobic metabolism can be exploited for the development of novel bioremediation strategies, enabling the degradation of recalcitrant pollutants in anaerobic environments.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusDorea
SpeciesDorea formicigenerans
StrainATCC 27755

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgastrointestinal tract
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Dorea formicigenerans ATCC 27755 D_formicigenerans-3.0.1_Cont400,

Gene Summary

Adenine Count

933098 bp

Thymine Count

947461 bp

Guanine Count

648231 bp

Cytosine Count

657241 bp

Genome Length

3186031 bp

Protein-coding Genes

3200 genes

Non-Coding Genes

167 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinDORFOR_03306Not AvailableNegative3144167 - 314579864138.3
hypothetical proteinDORFOR_03307Not AvailablePositive3145908 - 31460364614.63
hypothetical proteinDORFOR_03308Not AvailableNegative3146100 - 31463068017.6
nad dependent epimerase/dehydratase family proteinDORFOR_03309Not AvailableNegative3146451 - 314764444783.9
udp-n-acetylglucosamine 2-epimeraseDORFOR_03310Not AvailableNegative3147726 - 314891945048.3
vanz-like proteinDORFOR_03311Not AvailableNegative3149161 - 314962217603.3
sugar o-acyltransferase, sialic acid o-acetyltransferase neud familyDORFOR_03312Not AvailableNegative3149661 - 315023020632.5
polysaccharide biosynthesis proteinDORFOR_03313Not AvailableNegative3150235 - 315127838660.3
polysaccharide biosynthesis proteinDORFOR_03314Not AvailableNegative3151304 - 315258447752.2
bacterial transferase hexapeptide repeat proteinDORFOR_03315Not AvailableNegative3152587 - 315310818509.8

Displaying genes 3331 – 3340 of 3367 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

378 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001360methanesulfonateCH3O3SChemical structure of methanesulfonate59721-29-8
Average95.09Da
Monoisotopic94.980838711Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da

Displaying 1–10 of 378 metabolites

Health Effects

No health effects information available for this bacterium.