Cupriavidus necator H16

Gram-negativeRodMotileFacultative aerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Cupriavidus

Description

Cupriavidus necator H16 is a Gram-negative, rod-shaped bacterium recognized for its versatile metabolic capabilities, functioning as both a heterotroph and a chemoautotroph. This microbe thrives optimally at 30.0°C, demonstrating an ability to adapt to specialized habitats where it can utilize various energy sources. As a facultative aerobe, Cupriavidus necator H16 can grow in both the presence and absence of oxygen, which allows it to occupy diverse environmental niches and utilize different metabolic pathways depending on the availability of oxygen. The unique metabolic flexibility of Cupriavidus necator H16 enables it to engage in significant biogeochemical processes. Its capacity to perform chemoautotrophy suggests a role in carbon cycling, particularly in environments where organic carbon is limited. This trait may facilitate its survival and persistence in specialized habitats that are often subject to fluctuations in nutrient availability. Furthermore, the ability to switch between metabolic modes highlights its ecological adaptability, potentially contributing to its importance in bioremediation and bioenergy applications, where it may play a role in the degradation of pollutants or the production of biofuels. Overall, Cupriavidus necator H16 exemplifies the complexity of microbial life in specialized environments, showcasing how adaptability to energy sources and oxygen levels can influence ecological interactions and nutrient dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusCupriavidus
SpeciesCupriavidus necator
StrainH16

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Cupriavidus necator H16
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative aerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatSpecialized
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceHeterotroph - Chemoautotroph
PathogenicityNot Available

Genome Summary

Cupriavidus necator H16 chromosome 1, complete sequence.

Gene Summary

Adenine Count

676692 bp

Thymine Count

682120 bp

Guanine Count

1347607 bp

Cytosine Count

1345613 bp

Genome Length

4052032 bp

Protein-coding Genes

3764 genes

Non-Coding Genes

66 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
methionine synthaseH16_RS00725Not AvailablePositive163825 - 166572101080.0
hypothetical proteinH16_RS00730Not AvailablePositive166836 - 16729713694.0
response regulator transcription factorH16_RS00735Not AvailablePositive167608 - 16824023412.4
response regulatorH16_RS00740Not AvailablePositive168286 - 16869315185.3
chase3 domain-containing proteinH16_RS00745Not AvailableNegative168743 - 17014651523.0
duf1328 domain-containing proteinH16_RS33980Not AvailablePositive170431 - 1705985829.65
duf883 family proteinH16_RS00755Not AvailablePositive170651 - 17107915522.5
duf1840 domain-containing proteinH16_RS00760Not AvailableNegative171256 - 17157611525.9
arginine--trna ligaseH16_RS00765Not AvailablePositive171841 - 17362864728.4
spor domain-containing proteinH16_RS00770Not AvailablePositive173745 - 17447026343.4

Displaying genes 151 – 160 of 6893 in total

Metabolites

8 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001885Tetra-mu3-sulfido-tetrairon(1+)Fe4S4Chemical structure of Tetra-mu3-sulfido-tetrairon(1+)Not available
Average351.62Da
Monoisotopic351.62748Da
BASm0014037Fumaric acidC4H4O4Chemical structure of Fumaric acid110-17-8
Average116.0722Da
Monoisotopic116.010958616Da
BASm0014038Malic acidC4H6O5Chemical structure of Malic acid97-67-6
Average134.0874Da
Monoisotopic134.021523302Da
BASm0014042Oxoglutaric acidC5H6O5Chemical structure of Oxoglutaric acid328-50-7
Average146.0981Da
Monoisotopic146.021523302Da
BASm0017263NADPC21H29N7O17P3Chemical structure of NADP53-59-8
Average744.4129Da
Monoisotopic744.083277073Da
BASm0019271ferroheme bC34H30FeN4O4Chemical structure of ferroheme bNULL
Average614.485Da
Monoisotopic614.163836Da
BASm00345762Fe-2SFe2H8S6Chemical structure of 2Fe-2SNULL
Average312.11Da
Monoisotopic311.764899Da
BASm00345833Fe-4S iron-sulfur clusterFe3H4S4Chemical structure of 3Fe-4S iron-sulfur clusterNULL
Average299.81Da
Monoisotopic299.72549Da

Displaying 1–8 of 8 metabolites

Health Effects

No health effects information available for this bacterium.