Campylobacter hominis ATCC BAA-381

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Campylobacteraceae

Genus

Campylobacter

Description

Campylobacter hominis ATCC BAA-381 is a microbe that thrives in a mesophilic temperature range, specifically between 25°C and 37°C, placing it in the temperature preference category of "mesophilic". This microbe is a heterotroph, meaning it does not produce its own food, but rather obtains energy from the breakdown of organic compounds. C. hominis is also a chemoheterotroph, as it uses chemical energy from the oxidation of organic compounds to produce ATP. Gram-stained samples of C. hominis reveal a gram-negative staining pattern, indicating the presence of a thin peptidoglycan layer in the cell wall. The microbe's shape is typically spiral or comma-like, with a helical body and a flagellated phenotype. C. hominis can be found in various body sites, including the gastrointestinal tract, respiratory tract, and genitourinary tract, across all species. This microbe is an obligate aerobe, requiring the presence of oxygen for survival and growth. In terms of energy production, C. hominis is capable of using the Embden-Meyerhof-Parnas (EMP) pathway, also known as glycolysis, to produce ATP from glucose. This is in contrast to many other microbes that use different metabolic pathways, such as the pentose phosphate pathway or the citric acid cycle. One of the most distinctive features of C. hominis is its unique ability to infect humans, often causing gastrointestinal disease, particularly in individuals with compromised immune systems. Additionally, its ability to colonize various body sites, including the respiratory and genitourinary tracts, has significant implications for human health and disease. Despite being a relatively well-studied species, C. hominis remains a significant public health concern, and continued research is necessary to better understand its behavior and pathogenic potential.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyCampylobacteraceae
GenusCampylobacter
SpeciesCampylobacter hominis
StrainATCC BAA-381

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Campylobacter hominis ATCC BAA-381
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNo

Genome Summary

Campylobacter hominis ATCC BAA-381, complete sequence.

Gene Summary

Adenine Count

584347 bp

Thymine Count

583884 bp

Guanine Count

272383 bp

Cytosine Count

270658 bp

Genome Length

1711273 bp

Protein-coding Genes

1614 genes

Non-Coding Genes

64 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribosome hibernation-promoting factor, hpf/yfia familyCHAB381_RS02655Q49VV1Positive505491 - 50603320671.7
signal recognition particle proteinCHAB381_RS02660Q9ZK62Positive506246 - 50758049134.1
30s ribosomal protein s16CHAB381_RS02665A7I0V4Positive507642 - 5078698800.73
kh domain-containing proteinCHAB381_RS02670Not AvailablePositive507872 - 5081148996.06
ribosome maturation factor rimmCHAB381_RS02675A7I0V6Positive508107 - 50863720286.6
trna (guanosine(37)-n1)-methyltransferase trmdCHAB381_RS02680A7I0V7Positive508634 - 50933526794.6
50s ribosomal protein l19CHAB381_RS02685A7I0V8Positive509332 - 50968813541.6
ybgc/fadm family acyl-coa thioesteraseCHAB381_RS02690Q9ZLX8Positive510826 - 51121815114.3
efflux transporter outer membrane subunitCHAB381_RS02695Q8CWA4Negative511295 - 51274353308.2
efflux rnd transporter permease subunitCHAB381_RS02700Q8G2M6Negative512736 - 515900116206.0

Displaying genes 531 – 540 of 1681 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

409 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm00005275-oxopentanoateC5H7O3Chemical structure of 5-oxopentanoateNot available
Average115.109Da
Monoisotopic115.040067665Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00006473-hydroxypropanoateC3H5O3Chemical structure of 3-hydroxypropanoateNot available
Average89.071Da
Monoisotopic89.0244176Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da
BASm0000976enol-oxaloacetateC4H2O5Chemical structure of enol-oxaloacetateNot available
Average130.056Da
Monoisotopic129.9913203Da

Displaying 1–10 of 409 metabolites

Health Effects

Health ConditionRelationReference
Bacterial diarrheaCausesPMC9565744
Enteric diseaseCausesPMC9565744
CampylobacteriosisCausesPMC9565744
Clinical diarrheaCausesPMC9565744
Enteric diseaseCausesPMC9612815
DiarrheaCausesPMC9612815

Displaying health effects 1 – 6 of 6 in total