Escherichia coli O139:H28 str. E24377A

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli O139:H28 str. E24377A is a Gram-negative, rod-shaped bacterium that typically exists in pairs or as single cells. This strain demonstrates a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. Its optimal growth temperature is 37.0°C, which is consistent with the body temperature of warm-blooded hosts, indicating its adaptation to a host-associated habitat. As a member of the Enterobacteriaceae family, E. coli O139:H28 str. E24377A is often found within the intestinal tracts of mammals, where it plays a role in the complex microbial community. The facultative anaerobic nature of this strain suggests that it can efficiently utilize various metabolic pathways depending on the availability of oxygen, which may contribute to its survival in diverse environments within the host. The ecological insights provided by the traits of E. coli O139:H28 str. E24377A highlight its potential adaptability in fluctuating conditions within the host's gut. This adaptability may facilitate its persistence in the microbiome and underscore its significance in studies focusing on microbial interactions and host health. Further research could illuminate the specific roles this strain plays in gut ecology, nutrient cycling, and its interactions with other microbial species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainO139:H28 E24377A

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli O139:H28 str. E24377A
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Escherichia coli O139:H28 str. E24377A plasmid pETEC_35, complete

Gene Summary

Adenine Count

8231 bp

Thymine Count

8397 bp

Guanine Count

8279 bp

Cytosine Count

9460 bp

Genome Length

34367 bp

Protein-coding Genes

37 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

7

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
n-acetylneuraminate anomeraseECE24377A_RS20055Not AvailableNegative3699144 - 369960817038.7
n-acetylmannosamine kinaseECE24377A_RS20060Not AvailableNegative3699605 - 370048029658.6
n-acetylmannosamine-6-phosphate 2-epimeraseECE24377A_RS20065Not AvailableNegative3700477 - 370116624090.0
sialic acid transporter nantECE24377A_RS20070Not AvailableNegative3701214 - 370270453571.4
n-acetylneuraminate lyaseECE24377A_RS20075Not AvailableNegative3702813 - 370370632595.4
transcriptional regulator nanrECE24377A_RS20080Not AvailableNegative3703828 - 370461929526.0
anaerobic c4-dicarboxylate transporter dcucECE24377A_RS20085Not AvailablePositive3704999 - 370632147406.2
clpxp protease specificity-enhancing factorECE24377A_RS20090Not AvailableNegative3706364 - 370686118263.4
stringent starvation protein sspaECE24377A_RS20095Not AvailableNegative3706867 - 370750524306.3
30s ribosomal protein s9ECE24377A_RS20100Not AvailableNegative3707900 - 370829214857.1

Displaying genes 3971 – 3980 of 5202 in total

Metabolites

1840 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000893crotonobetaineC7H13NO2Chemical structure of crotonobetaine927-89-9
Average143.1836Da
Monoisotopic143.0946287Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da

Displaying 1–10 of 1840 metabolites

Health Effects

No health effects information available for this bacterium.