Coprothermobacter proteolyticus DSM 5265

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Coprothermobacterota

Class

Coprothermobacteria

Order

Coprothermobacterales

Family

Coprothermobacteraceae

Genus

Coprothermobacter

Description

Coprothermobacter proteolyticus (strain ATCC 35245 / DSM 5265 / BT) is a rod-shaped, anaerobic, thermophilic proteolytic, Gram-positive bacterium isolated from a thermophilic digestor that was fermenting tannery wastes and cattle manure. This organism was originally classified as Thermobacteroides proteolyticus and subsequently assigned to the new genus of Coprothermobacter. C. proteolyticus has an optimum temperature for growth of 63 degrees Celsius. It is phylogenetically related (96.3 % sequence similarity) to Coprothermobacter platensis (a moderately thermophilic bacterium), and both show similar morphology and fermentation products. Both can reduce thiosulfate to sulfide with glucose as substrate. The thiosulfate addition clearly stimulates glucose utilization and growth. Anaerobic digestion is increasingly used for carbon decontamination of agroindustrial wastewaters. Proteins are frequently a major component of'such wastes, and their degradation, initiated by extracellular proteases, is often incomplete. The vast majority of full-scale digestors are mesophilic, however thermophilic treatment is also being explored as it may have advantages, especially for effluents produced at high temperature (adapted from PubMed 9828430). (EBI Integr8)

Taxonomy

KingdomPseudomonadati
PhylumCoprothermobacterota
ClassCoprothermobacteria
OrderCoprothermobacterales
FamilyCoprothermobacteraceae
GenusCoprothermobacter
SpeciesCoprothermobacter proteolyticus
StrainDSM 5265

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Coprothermobacter proteolyticus DSM 5265
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature63
Temperature rangeThermophilic
HabitatSpecialized
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNo

Genome Summary

Coprothermobacter proteolyticus DSM 5265, complete sequence.

Gene Summary

Adenine Count

395614 bp

Thymine Count

391363 bp

Guanine Count

323716 bp

Cytosine Count

314219 bp

Genome Length

1424912 bp

Protein-coding Genes

1419 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
methionine synthaseCOPRO5265_RS00055Not AvailablePositive10707 - 1127021422.9
homocysteine s-methyltransferase family proteinCOPRO5265_RS00060Not AvailablePositive11267 - 1359484967.3
aspartate kinaseCOPRO5265_RS00065Not AvailablePositive13591 - 1494049133.0
homocysteine biosynthesis proteinCOPRO5265_RS00070Not AvailablePositive14937 - 1626848530.5
upf0280 family proteinCOPRO5265_RS00075Not AvailablePositive16255 - 1700727163.5
methylenetetrahydrofolate reductaseCOPRO5265_RS00080Not AvailablePositive16994 - 1795035945.6
aspartate-semialdehyde dehydrogenaseCOPRO5265_RS00085Not AvailablePositive17980 - 1901437445.2
rna polymerase sigma factorCOPRO5265_RS00090Not AvailablePositive19380 - 1992221426.3
hypothetical proteinCOPRO5265_RS00095Not AvailablePositive19906 - 2066727768.9
abc transporter atp-binding proteinCOPRO5265_RS00100Not AvailablePositive20667 - 2153632293.3

Displaying genes 11 – 20 of 916 in total

Metabolites

171 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0001142butanoateC4H7O2Chemical structure of butanoateNot available
Average87.099Da
Monoisotopic87.045153045Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0001808corynebactinC39H42N6O18Chemical structure of corynebactinNot available
Average882.789Da
Monoisotopic882.2555585Da
BASm0001861(2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diolC12H12O2Chemical structure of (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diolNot available
Average188.226Da
Monoisotopic188.0837296Da

Displaying 1–10 of 171 metabolites

Health Effects

No health effects information available for this bacterium.