Legionella pneumophila str. Lens

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila is the causative agent of the Legionnaires' disease, a potentially fatal pneumonia. It was isolated after an outbreak of pneumonia at an American legion convention in Philadelphia. Legionella pneumophila is found in biofilms and fresh and industrial water systems worldwide. It can survive and replicate intracellularly in free-living protozoa, often in aquatic biofilms. Legionella pneumophila (strain Corby) is an aerobic human isolate. (HAMAP: LEGPC)

Taxonomy

Kingdom	Pseudomonadati
Phylum	Pseudomonadota
Class	Gammaproteobacteria
Order	Legionellales
Family	Legionellaceae
Genus	Legionella
Species	Legionella pneumophila
Strain	Lens

Profile

Physiology
Gram staining properties	Negative
Shape	Rod
Mobility	Yes
Flagellar presence	Yes
Number of membranes	2

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Aerobe
Optimal temperature	Not Available
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Not Available
Cell arrangement	Singles
Sporulation	Nonsporulating
Energy source	Chemoorganotroph
Pathogenicity	Yes

Genome Summary

Legionella pneumophila str. Lens, complete sequence.

NC_006369.1

Gene Summary

Adenine Count

1035561 bp

Thymine Count

1024760 bp

Guanine Count

645845 bp

Cytosine Count

639400 bp

Genome Length

3345687 bp

Protein-coding Genes

2926 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
transcription antitermination factor nusb	LPL_RS03845	Not Available	Positive	868385 - 868828	16969.4
thiamine-phosphate kinase	LPL_RS03850	Not Available	Positive	868821 - 869777	34722.0
phosphatidylglycerophosphatase a	LPL_RS03855	Not Available	Positive	869867 - 870349	18119.6
ai-2e family transporter	LPL_RS03860	Not Available	Positive	870349 - 871401	38656.7
hypothetical protein	LPL_RS03865	Not Available	Negative	871393 - 872130	26351.2
outer membrane protein	LPL_RS03870	Not Available	Negative	872140 - 872778	23360.3
dot/icm t4ss effector ravh	LPL_RS03875	Not Available	Positive	872941 - 874389	55191.5
nad+ synthase	LPL_RS03880	Not Available	Negative	874441 - 876051	59908.4
dead/deah box helicase	LPL_RS03885	Not Available	Positive	876342 - 879608	125740.0
duf2147 domain-containing protein	LPL_RS03890	Not Available	Positive	879878 - 880312	15553.1

Displaying genes 781 – 790 of 2982 in total

Pathways

1415 pathways

2,3-Dihydroxybenzoate Biosynthesis

Biosynthesis of Siderophore Group Nonribosomal Peptides

Palmitate Biosynthesis

Show All 1415 Pathways

Metabolite ID	Metabolite name	CAS number	Average mass Monoisotopic mass
BASm0000237	(R)-4'-phosphopantothenateC9H18NO8P	Not available	Average299.2149Da Monoisotopic299.0770031Da
BASm0000251	2-dehydropantoateC6H9O4	Not available	Average145.1333Da Monoisotopic145.050083776Da
BASm0000253	2-oxopent-4-enoateC5H5O3	Not available	Average113.093Da Monoisotopic113.024417601Da
BASm0000260	3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5	Not available	Average405.556Da Monoisotopic405.264647871Da
BASm0000377	(S)-malateC4H4O5	Not available	Average132.0716Da Monoisotopic132.005873238Da
BASm0000387	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6	Not available	Average455.432Da Monoisotopic455.1564286Da
BASm0000401	(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8	Not available	Average286.218Da Monoisotopic286.0579371Da
BASm0000428	3-oxoadipateC6H6O5	Not available	Average158.11Da Monoisotopic158.022620453Da
BASm0000553	biphenyl-2,3-diolC12H10O2	Not available	Average186.2066Da Monoisotopic186.0680796Da
BASm0000592	(S)-1-phenylethanolC8H10O	Not available	Average122.1644Da Monoisotopic122.0731649Da