Bacteroides fragilis YCH46

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis YCH46 is an anaerobic, Gram-negative, rod-shaped bacterium that thrives in human intestines, exhibiting a temperature preference for mesophilic conditions and functioning as a chemoheterotroph, utilizing organic compounds for energy production. This microbe is predominantly found in the gastrointestinal tract, where it plays a critical role in maintaining gut health, contributing to the complex microbiome that aids in digestion and nutrient absorption. As a mesophile, Bacteroides fragilis YCH46 grows optimally at moderate temperatures, which aligns with the conditions of the human body. Its classification as a chemoheterotroph indicates that it derives energy from organic substrates, metabolizing a variety of carbohydrates and proteins. This metabolic versatility allows it to thrive in the nutrient-rich environment of the intestines, where it can break down complex polysaccharides, contributing to the fermentation process and producing short-chain fatty acids that are beneficial for colon health. The Gram-negative characteristic of Bacteroides fragilis YCH46 is significant, as it possesses an outer membrane that contributes to its resistance against certain antibiotics. Its rod shape enhances its ability to colonize the intestinal mucosa, facilitating interactions with host tissues and other microbial species.Bacteroides fragilis YCH46 also plays a role in modulating the immune response, helping to maintain a balanced gut microbiota. An imbalance of this microbe has been associated with various gastrointestinal disorders, highlighting its importance in health and disease. Its ability to produce bacteriocins may also provide a competitive advantage against pathogenic bacteria, contributing to the overall stability of the gut ecosystem.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
StrainYCH46

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis YCH46
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Bacteroides fragilis YCH46 plasmid pBFY46, complete sequence.

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
family 16 glycoside hydrolaseBF_RS01755Q8VZR2Positive423974 - 42637390070.2
glycoside hydrolase family 78 proteinBF_RS01760T2KPL4Positive426383 - 429022100692.0
m20 family metallo-hydrolaseBF_RS01765B4F192Negative429202 - 43026339014.8
long-chain fatty acid--coa ligaseBF_RS01770Not AvailablePositive430452 - 43225768418.5
peptide chain release factor 2BF_RS01775Q7WK44Positive432318 - 43343442616.2
hypothetical proteinBF_RS22605Not AvailablePositive433587 - 4337214885.33
opro/oprp family phosphate-selective porinBF_RS01780Not AvailablePositive433838 - 43515748629.4
cyth domain-containing proteinBF_RS01785A3DIJ8Positive435165 - 43563517796.1
duf4010 domain-containing proteinBF_RS01790Not AvailablePositive435692 - 43698747939.9
outer membrane beta-barrel family proteinBF_RS01795Not AvailablePositive437158 - 43973495344.9

Displaying genes 451 – 460 of 1179 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
AbscessesCausesPMC1887533
Soft tissue infections of the gastrointestinal tractCausesPMC1887533
Diarrheal diseasesCausesPMC1887533

Displaying health effects 1 – 3 of 3 in total