Bacteroides fragilis YCH46

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis YCH46 is an anaerobic, Gram-negative, rod-shaped bacterium that thrives in human intestines, exhibiting a temperature preference for mesophilic conditions and functioning as a chemoheterotroph, utilizing organic compounds for energy production. This microbe is predominantly found in the gastrointestinal tract, where it plays a critical role in maintaining gut health, contributing to the complex microbiome that aids in digestion and nutrient absorption. As a mesophile, Bacteroides fragilis YCH46 grows optimally at moderate temperatures, which aligns with the conditions of the human body. Its classification as a chemoheterotroph indicates that it derives energy from organic substrates, metabolizing a variety of carbohydrates and proteins. This metabolic versatility allows it to thrive in the nutrient-rich environment of the intestines, where it can break down complex polysaccharides, contributing to the fermentation process and producing short-chain fatty acids that are beneficial for colon health. The Gram-negative characteristic of Bacteroides fragilis YCH46 is significant, as it possesses an outer membrane that contributes to its resistance against certain antibiotics. Its rod shape enhances its ability to colonize the intestinal mucosa, facilitating interactions with host tissues and other microbial species.Bacteroides fragilis YCH46 also plays a role in modulating the immune response, helping to maintain a balanced gut microbiota. An imbalance of this microbe has been associated with various gastrointestinal disorders, highlighting its importance in health and disease. Its ability to produce bacteriocins may also provide a competitive advantage against pathogenic bacteria, contributing to the overall stability of the gut ecosystem.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
StrainYCH46

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis YCH46
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Bacteroides fragilis YCH46 plasmid pBFY46, complete sequence.

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
2,3-bisphosphoglycerate-independent phosphoglycerate mutaseBF_RS01390Q64ZN5Positive320496 - 32201055635.9
hamp domain-containing sensor histidine kinaseBF_RS01395Q38846Positive322159 - 32325341325.4
histidine kinase dimerization/phospho-acceptor domain-containing proteinBF_RS01400Not AvailablePositive323250 - 32519374924.9
duf3109 family proteinBF_RS01405Not AvailablePositive325548 - 32612921991.4
asma family proteinBF_RS01410Not AvailablePositive326126 - 329092110089.0
dna topoisomerase (atp-hydrolyzing) subunit bBF_RS01415P94604Negative329193 - 33115173156.8
30s ribosomal protein s20BF_RS01420Q5LIK4Negative331331 - 3315859761.11
Trna-gluNot AvailableNot AvailablePositive331622 - 331696Not Available
dna repair protein recoBF_RS01430Q5LIK3Positive331996 - 33272428278.4
gatb/yqey domain-containing proteinBF_RS01435P54464Negative332834 - 33328316023.5

Displaying genes 381 – 390 of 1179 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
AbscessesCausesPMC1887533
Soft tissue infections of the gastrointestinal tractCausesPMC1887533
Diarrheal diseasesCausesPMC1887533

Displaying health effects 1 – 3 of 3 in total