Bacteroides fragilis YCH46

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis YCH46 is an anaerobic, Gram-negative, rod-shaped bacterium that thrives in human intestines, exhibiting a temperature preference for mesophilic conditions and functioning as a chemoheterotroph, utilizing organic compounds for energy production. This microbe is predominantly found in the gastrointestinal tract, where it plays a critical role in maintaining gut health, contributing to the complex microbiome that aids in digestion and nutrient absorption. As a mesophile, Bacteroides fragilis YCH46 grows optimally at moderate temperatures, which aligns with the conditions of the human body. Its classification as a chemoheterotroph indicates that it derives energy from organic substrates, metabolizing a variety of carbohydrates and proteins. This metabolic versatility allows it to thrive in the nutrient-rich environment of the intestines, where it can break down complex polysaccharides, contributing to the fermentation process and producing short-chain fatty acids that are beneficial for colon health. The Gram-negative characteristic of Bacteroides fragilis YCH46 is significant, as it possesses an outer membrane that contributes to its resistance against certain antibiotics. Its rod shape enhances its ability to colonize the intestinal mucosa, facilitating interactions with host tissues and other microbial species.Bacteroides fragilis YCH46 also plays a role in modulating the immune response, helping to maintain a balanced gut microbiota. An imbalance of this microbe has been associated with various gastrointestinal disorders, highlighting its importance in health and disease. Its ability to produce bacteriocins may also provide a competitive advantage against pathogenic bacteria, contributing to the overall stability of the gut ecosystem.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
StrainYCH46

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis YCH46
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityYes

Genome Summary

Bacteroides fragilis YCH46 plasmid pBFY46, complete sequence.

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

Not Available

Non-Coding Genes

Not Available

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphoribosylamine--glycine ligaseBF_RS00395Q9KV81Negative91151 - 9242545729.2
dpp iv n-terminal domain-containing proteinBF_RS00400Q7MUW6Negative92447 - 9459180737.2
class i sam-dependent rna methyltransferaseBF_RS00405Q55156Negative94742 - 9608251402.1
serine o-acetyltransferaseBF_RS00410Q59967Negative96160 - 9705932561.2
histidine kinaseBF_RS00415P94513Positive97186 - 9921678568.5
lyttr family dna-binding domain-containing proteinBF_RS00420Q9KU36Positive99229 - 9998429091.7
duf3836 domain-containing proteinBF_RS00425Not AvailableNegative100360 - 10075515288.1
dna polymerase iBF_RS00430P00582Negative101025 - 103832106409.0
polyprenyl synthetase family proteinBF_RS00435O24743Positive103918 - 10489236083.4
duf1266 domain-containing proteinBF_RS00440Not AvailableNegative104902 - 10560927280.8

Displaying genes 181 – 190 of 1179 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
AbscessesCausesPMC1887533
Soft tissue infections of the gastrointestinal tractCausesPMC1887533
Diarrheal diseasesCausesPMC1887533

Displaying health effects 1 – 3 of 3 in total