Legionella pneumophila subsp. pneumophila str. Philadelphia 1

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila is the causative agent of the Legionnaires' disease, a potentially fatal pneumonia. It was isolated after an outbreak of pneumonia at an American legion convention in Philadelphia. Legionella pneumophila is found in biofilms and fresh and industrial water systems worldwide. It can survive and replicate intracellularly in free-living protozoa, often in aquatic biofilms. Legionella pneumophila (strain Corby) is an aerobic human isolate. (HAMAP: LEGPC)

Taxonomy

Kingdom	Pseudomonadati
Phylum	Pseudomonadota
Class	Gammaproteobacteria
Order	Legionellales
Family	Legionellaceae
Genus	Legionella
Species	Legionella pneumophila
Strain	Philadelphia 1

Profile

Physiology
Gram staining properties	Negative
Shape	Rod
Mobility	Yes
Flagellar presence	Yes
Number of membranes	2

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Aerobe
Optimal temperature	Not Available
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Free living
Host(s)	Not Available
Cell arrangement	Singles
Sporulation	Nonsporulating
Energy source	Chemoorganotroph
Pathogenicity	Yes

Genome Summary

Legionella pneumophila subsp. pneumophila str. Philadelphia 1,

NC_002942.5

Gene Summary

Adenine Count

1048939 bp

Thymine Count

1048510 bp

Guanine Count

651691 bp

Cytosine Count

648613 bp

Genome Length

3397754 bp

Protein-coding Genes

2995 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
lpg2844 family dot/icm t4ss effector	LPG_RS14345	Not Available	Negative	3218707 - 3219792	36077.2
carboxylesterase	LPG_RS14350	Not Available	Positive	3220428 - 3221213	29167.7
hypothetical protein	LPG_RS14355	Not Available	Positive	3221360 - 3221593	8637.07
gin domain-containing protein	LPG_RS14360	Not Available	Negative	3221661 - 3222623	36049.5
ribonuclease t2 family protein	LPG_RS14365	Not Available	Negative	3222761 - 3223741	36845.7
class i sam-dependent methyltransferase	LPG_RS14370	Not Available	Positive	3223904 - 3225208	49875.9
cold-shock protein	LPG_RS14375	Not Available	Negative	3225308 - 3225523	7929.36
fad-dependent oxidoreductase	LPG_RS14380	Not Available	Negative	3225763 - 3227220	55132.0
amidase	LPG_RS14385	Not Available	Negative	3227502 - 3228884	50566.5
batd family protein	LPG_RS14390	Not Available	Negative	3229121 - 3230770	61546.2

Displaying genes 2881 – 2890 of 3051 in total

Pathways

1411 pathways

2,3-Dihydroxybenzoate Biosynthesis

Biosynthesis of Siderophore Group Nonribosomal Peptides

Palmitate Biosynthesis

Show All 1411 Pathways

Metabolite ID	Metabolite name	CAS number	Average mass Monoisotopic mass
BASm0000237	(R)-4'-phosphopantothenateC9H18NO8P	Not available	Average299.2149Da Monoisotopic299.0770031Da
BASm0000251	2-dehydropantoateC6H9O4	Not available	Average145.1333Da Monoisotopic145.050083776Da
BASm0000253	2-oxopent-4-enoateC5H5O3	Not available	Average113.093Da Monoisotopic113.024417601Da
BASm0000260	3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5	Not available	Average405.556Da Monoisotopic405.264647871Da
BASm0000377	(S)-malateC4H4O5	Not available	Average132.0716Da Monoisotopic132.005873238Da
BASm0000387	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6	Not available	Average455.432Da Monoisotopic455.1564286Da
BASm0000401	(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8	Not available	Average286.218Da Monoisotopic286.0579371Da
BASm0000428	3-oxoadipateC6H6O5	Not available	Average158.11Da Monoisotopic158.022620453Da
BASm0000553	biphenyl-2,3-diolC12H10O2	Not available	Average186.2066Da Monoisotopic186.0680796Da
BASm0000592	(S)-1-phenylethanolC8H10O	Not available	Average122.1644Da Monoisotopic122.0731649Da