Burkholderia pseudomallei K96243

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Burkholderia

Description

Burkholderia pseudomallei strain K96243. This strain was a clinical isolate from Thailand. The genome of this organism carries many genomic islands as compared to the related organism B. mallei, suggesting extensive horizontal transfer. Three different type III secretion systems (TTSS) are encoded on the chromosomes of this organism, two of which are similar to plant pathogenic TTSSs, while the third is similar to the Salmonella pathogenicity island, all of which may contribute to pathogenicity. Other virulence determinants include multidrug efflux pumps, secreted toxins and proteases, and various adhesins. Capsular polysaccharide may protect the organism from host defense mechanisms. This organism also carries a number of small sequence repeats which may promoter antigenic variation, similar to what was found with the B. mallei genome. (NCBI BioProject: bp_list[1])

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusBurkholderia
SpeciesBurkholderia pseudomallei
StrainK96243

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Burkholderia pseudomallei K96243
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatTerrestrial
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Burkholderia pseudomallei K96243 chromosome 2, complete sequence.

Gene Summary

Adenine Count

501425 bp

Thymine Count

498269 bp

Guanine Count

1081855 bp

Cytosine Count

1091456 bp

Genome Length

3173005 bp

Protein-coding Genes

2631 genes

Non-Coding Genes

81 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter substrate-binding proteinBPS_RS19335Not AvailableNegative180870 - 18181732864.5
sugar abc transporter permeaseBPS_RS19340Not AvailableNegative181894 - 18292835458.2
sugar abc transporter atp-binding proteinBPS_RS19345Not AvailableNegative182971 - 18452455255.1
rok family proteinBPS_RS19350Not AvailableNegative184511 - 18576144168.0
hypothetical proteinBPS_RS19355Not AvailableNegative186303 - 18666811906.4
glycoside hydrolase family 15 proteinBPS_RS19360Not AvailableNegative186668 - 18931693573.4
atp-dependent rna helicase dbpaBPS_RS19365Not AvailableNegative190115 - 19151250961.6
porinBPS_RS19370Not AvailableNegative191677 - 19230622570.1
mfs transporterBPS_RS19375Not AvailableNegative192341 - 19365445379.9
m20 aminoacylase family proteinBPS_RS19380Not AvailableNegative193695 - 19488542119.6

Displaying genes 241 – 250 of 6507 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

79 records
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Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000234(3R)-hydroxybutanoate dimerC8H13O5Chemical structure of (3R)-hydroxybutanoate dimerNot available
Average189.188Da
Monoisotopic189.0768471Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001691hydrogenselenideHSeChemical structure of hydrogenselenideNot available
Average79.98Da
Monoisotopic80.924896Da
BASm0001845nicotinateC6H4NO2Chemical structure of nicotinateNot available
Average122.1015Da
Monoisotopic122.0242034Da

Displaying 1–10 of 79 metabolites

Health Effects

No health effects information available for this bacterium.