Methylobacillus flagellatus KT

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Nitrosomonadales

Family

Methylophilaceae

Genus

Methylobacillus

Description

Methylobacillus flagellatus strain KT. This organism contains multiple formaldehyde degradation pathways including a ribulose monophosphate (RMP) cycle and a linear pathway utilizing tetrahydromethanopterin-dependent enzymes. Degradation of formaldehydge is part of the process of incorporating carbon into the cell, and as this organism is an obligate methylotroph and can only utilize methanol and methylamine as the sole carbon and energy sources, conversion of intermediates is both an important part of the growth of cell and an exploitable process for industrial purposes. This strain was isolated from activated sludge found at the wastewater treatment plant in Moscow, Russia and is the fastest growing methylotroph discovered. The fast growth and conversion rate make it useful in industrial production of biomolecules. (NCBI BioProject: bp_list[1])

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNitrosomonadales
FamilyMethylophilaceae
GenusMethylobacillus
SpeciesMethylobacillus flagellatus
StrainKT

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Methylobacillus flagellatus KT
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatSpecialized
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNo

Genome Summary

Methylobacillus flagellatus KT, complete sequence.

Gene Summary

Adenine Count

656439 bp

Thymine Count

659376 bp

Guanine Count

826742 bp

Cytosine Count

828960 bp

Genome Length

2971517 bp

Protein-coding Genes

2785 genes

Non-Coding Genes

92 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dha2 family efflux mfs transporter permease subunitMFLA_RS02675Not AvailablePositive545168 - 54661350602.5
gnat family n-acetyltransferaseMFLA_RS02680Not AvailableNegative546674 - 54712317014.3
3-deoxy-7-phosphoheptulonate synthase arogMFLA_RS02685Not AvailableNegative547202 - 54828439492.1
hypothetical proteinMFLA_RS02690Not AvailableNegative548425 - 54885015476.3
duf481 domain-containing proteinMFLA_RS02695Not AvailablePositive549238 - 55027838673.2
hypothetical proteinMFLA_RS02700Not AvailableNegative550285 - 5504797217.33
eal domain-containing proteinMFLA_RS02705Not AvailablePositive550682 - 55325895031.5
diguanylate cyclaseMFLA_RS02710Not AvailablePositive553294 - 55513868364.2
pqq-dependent sugar dehydrogenaseMFLA_RS02715Not AvailablePositive555236 - 55650447551.2
response regulator transcription factorMFLA_RS02720Not AvailableNegative556552 - 55721125052.6

Displaying genes 601 – 610 of 2877 in total

Metabolites

1806 records
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Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da

Displaying 1–10 of 1806 metabolites

Health Effects

No health effects information available for this bacterium.