Ehrlichia ruminantium str. Welgevonden

Gram-negativeCocciNon-motile

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Alphaproteobacteria

Order

Rickettsiales

Family

Anaplasmataceae

Genus

Ehrlichia

Description

Ehrlichia ruminantium is the causative agent of the heartwater disease that affects domestic and wild ruminants. The bacterium is transmitted by ticks of the genus Amblyomma. The disease is present throughout subsaharan Africa and on several Caribbean islands where it represents a major constraint to livestock production. It threatens to invade the Americas. Heartwater is characterized by fever, nervous signs, hydropericardium, hydrothorax, ascites, edema of the lungs, and high mortality. Its name comes from hydropericardium (an excessive amount of fluid within the sac surrounding the heart), which is commonly observed with this disease.(From http://www.expasy.org/sprot/hamap/EHRRG.html) (BacMap)

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassAlphaproteobacteria
OrderRickettsiales
FamilyAnaplasmataceae
GenusEhrlichia
SpeciesEhrlichia ruminantium
StrainWelgevonden

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Ehrlichia ruminantium str. Welgevonden
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNo?

Genome Summary

Ehrlichia ruminantium str. Welgevonden, complete sequence.

Gene Summary

Adenine Count

551361 bp

Thymine Count

545867 bp

Guanine Count

205035 bp

Cytosine Count

210714 bp

Genome Length

1512977 bp

Protein-coding Genes

950 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase foldERWE_RS03590Not AvailableNegative1117963 - 111886532426.6
guanylate kinaseERWE_RS03595Not AvailableNegative1120324 - 112095324377.4
heme abc transporter permeaseERWE_RS03600Not AvailablePositive1122722 - 112342626617.6
holliday junction branch migration protein ruvaERWE_RS03605Not AvailablePositive1123437 - 112401221514.2
holliday junction branch migration dna helicase ruvbERWE_RS03610Not AvailablePositive1125173 - 112616237107.9
hypothetical proteinERWE_RS03615Not AvailablePositive1126140 - 11263739223.28
multidrug effflux mfs transporterERWE_RS03620Not AvailableNegative1129104 - 113030044328.0
fad-dependent thymidylate synthaseERWE_RS03625Not AvailableNegative1131630 - 113248733308.7
succinate dehydrogenase iron-sulfur subunitERWE_RS03630Not AvailableNegative1134249 - 113502529616.5
succinate dehydrogenase flavoprotein subunitERWE_RS03635Not AvailableNegative1135059 - 113685565588.4

Displaying genes 741 – 750 of 993 in total

Metabolites

1587 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–10 of 1587 metabolites

Health Effects

No health effects information available for this bacterium.