Burkholderia mallei ATCC 23344

Gram-negativeRodNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Burkholderiaceae

Genus

Burkholderia

Description

Burkholderia mallei is the etiologic agent of glanders, a disease that is often fatal. Its natural reservoir are horses and other equines, but it can be occasionally transmitted to humans either by inhalation or through breaks in the skin. It is an obligate animal pathogen, with an intracellular localization. B. mallei is highly infectious as an aerosol and was used as a biological weapon in the American Civil War and in both World Wars. Unlike the related bacterium B.pseudomallei it is non-motile. One of its virulence factors has been identified as the type III secretion system, another as the newly characterized type VI (T6S). Strain NCTC 10229 will be used for comparative genomics. (EBI Integr8)

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyBurkholderiaceae
GenusBurkholderia
SpeciesBurkholderia mallei
StrainATCC 23344

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Burkholderia mallei ATCC 23344
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Burkholderia mallei ATCC 23344 chromosome 1, complete sequence.

Gene Summary

Adenine Count

559281 bp

Thymine Count

558552 bp

Guanine Count

1185888 bp

Cytosine Count

1206427 bp

Genome Length

3510148 bp

Protein-coding Genes

3222 genes

Non-Coding Genes

55 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
d-amino acid aminotransferaseBMA_RS00240Not AvailableNegative63859 - 6480634256.9
d-alanyl-d-alanine carboxypeptidase family proteinBMA_RS00245Not AvailableNegative64896 - 6620946452.2
alpha/beta hydrolaseBMA_RS00250Not AvailableNegative66975 - 6761922980.8
(2fe-2s) ferredoxin domain-containing proteinBMA_RS00255Not AvailableNegative67666 - 6798011941.1
vanz family proteinBMA_RS00260Not AvailableNegative68097 - 6929642765.3
abc-type transport auxiliary lipoprotein family proteinBMA_RS00265Not AvailableNegative69328 - 6996621901.0
mlad family proteinBMA_RS00270Not AvailableNegative69985 - 7091432887.4
abc transporter atp-binding proteinBMA_RS00275Not AvailableNegative70938 - 7178030490.1
mlae family abc transporter permeaseBMA_RS00280Not AvailableNegative71777 - 7290140003.8
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidaseBMA_RS00285Not AvailablePositive73171 - 7523172923.4

Displaying genes 51 – 60 of 5292 in total

Metabolites

2303 records
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Mass search
Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000198tetracenomycin CC23H20O11Chemical structure of tetracenomycin CNot available
Average472.402Da
Monoisotopic472.100561464Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000234(3R)-hydroxybutanoate dimerC8H13O5Chemical structure of (3R)-hydroxybutanoate dimerNot available
Average189.188Da
Monoisotopic189.0768471Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da

Displaying 1–10 of 2303 metabolites

Health Effects

No health effects information available for this bacterium.