Akkermansia muciniphila str. CBA5201

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila str. CBA5201 is a Gram-negative, anaerobic bacterium characterized by its cocci shape, which typically arranges in pairs or singles. This strain thrives optimally at a temperature of 37.0°C, reflecting its adaptation to host-associated environments. Akkermansia muciniphila is known for its role in the gut microbiota, where it contributes to the degradation of mucin, a key component of the intestinal mucus layer. As an anaerobe, A. muciniphila str. CBA5201 is well-suited to the low-oxygen conditions prevalent in the gastrointestinal tract, allowing it to thrive in this niche while potentially influencing host health through its metabolic activities. Notably, its presence in the gut microbiome may play a crucial role in maintaining the integrity of the mucosal barrier, suggesting its involvement in the host's immune response and overall metabolic homeostasis. The unique ability of Akkermansia muciniphila to utilize mucin as a carbon source underscores its potential significance in the modulation of gut health and its impact on host-microbe interactions. Further exploration of its functional capacity may provide insights into its contributions to gut ecology and its implications for host well-being.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainCBA5201

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila str. CBA5201
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain CBA5201 chromosome, complete

Gene Summary

Adenine Count

641282 bp

Thymine Count

636655 bp

Guanine Count

789726 bp

Cytosine Count

792744 bp

Genome Length

2860407 bp

Protein-coding Genes

2366 genes

Non-Coding Genes

66 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l24AKKM5201_RS04255Not AvailableNegative972990 - 9732177991.77
nad(+)/nadh kinaseAKKM5201_RS04260Not AvailableNegative973441 - 97431331380.3
septal ring lytic transglycosylase rlpa family proteinAKKM5201_RS04265Not AvailablePositive974463 - 97496618636.6
bifunctional metallophosphatase/5'-nucleotidaseAKKM5201_RS04270Not AvailablePositive975009 - 97646653615.7
dead/deah box helicaseAKKM5201_RS04275Not AvailablePositive976504 - 97919199396.0
gfo/idh/moca family proteinAKKM5201_RS04280Not AvailableNegative979265 - 98068651829.3
hypothetical proteinAKKM5201_RS04285Not AvailablePositive980852 - 98186839172.2
Ncrna_class:srp_rnaNot AvailableNot AvailablePositive981920 - 982014Not Available
bifunctional folylpolyglutamate synthase/dihydrofolate synthaseAKKM5201_RS04295Not AvailablePositive982080 - 98329443570.6
u32 family peptidaseAKKM5201_RS04300Not AvailablePositive983321 - 98582891950.6

Displaying genes 861 – 870 of 2432 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total