Akkermansia muciniphila str. CBA5201

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila str. CBA5201 is a Gram-negative, anaerobic bacterium characterized by its cocci shape, which typically arranges in pairs or singles. This strain thrives optimally at a temperature of 37.0°C, reflecting its adaptation to host-associated environments. Akkermansia muciniphila is known for its role in the gut microbiota, where it contributes to the degradation of mucin, a key component of the intestinal mucus layer. As an anaerobe, A. muciniphila str. CBA5201 is well-suited to the low-oxygen conditions prevalent in the gastrointestinal tract, allowing it to thrive in this niche while potentially influencing host health through its metabolic activities. Notably, its presence in the gut microbiome may play a crucial role in maintaining the integrity of the mucosal barrier, suggesting its involvement in the host's immune response and overall metabolic homeostasis. The unique ability of Akkermansia muciniphila to utilize mucin as a carbon source underscores its potential significance in the modulation of gut health and its impact on host-microbe interactions. Further exploration of its functional capacity may provide insights into its contributions to gut ecology and its implications for host well-being.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainCBA5201

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila str. CBA5201
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain CBA5201 chromosome, complete

Gene Summary

Adenine Count

641282 bp

Thymine Count

636655 bp

Guanine Count

789726 bp

Cytosine Count

792744 bp

Genome Length

2860407 bp

Protein-coding Genes

2366 genes

Non-Coding Genes

66 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tyrosine--trna ligaseAKKM5201_RS01095Not AvailableNegative245878 - 24705944349.9
hypothetical proteinAKKM5201_RS01100Not AvailableNegative247324 - 2475488588.11
dmt family proteinAKKM5201_RS01105Not AvailableNegative247608 - 24797013711.3
abc transporter permeaseAKKM5201_RS01110Not AvailableNegative247989 - 24894534684.1
abc transporter permeaseAKKM5201_RS01115Not AvailableNegative248942 - 24985632742.0
peptide abc transporter substrate-binding proteinAKKM5201_RS01120Not AvailableNegative249862 - 25172169715.8
thioredoxin family proteinAKKM5201_RS01125Not AvailableNegative251986 - 25295134935.1
saccharopine dehydrogenase family proteinAKKM5201_RS01130Not AvailablePositive253163 - 25439245847.8
metallophosphoesterase family proteinAKKM5201_RS01135Not AvailablePositive254622 - 25558136024.3
hypothetical proteinAKKM5201_RS01140Not AvailableNegative255707 - 25663335554.7

Displaying genes 221 – 230 of 2432 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total