Akkermansia muciniphila str. EB-AMDK-17

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain EB-AMDK-17 is a Gram-negative, anaerobic coccus that primarily exists in pairs or as single cells. This strain thrives optimally at a temperature of 37.0°C, suggesting its adaptation to a host-associated environment, likely reflecting its role in the gastrointestinal tract of various organisms. As a member of the Akkermansia genus, this strain is known to be involved in the metabolism of mucin, a glycoprotein component of mucus, which indicates a specialized niche within the mucosal layer of the gut. The ability to thrive in anaerobic conditions further emphasizes its adaptation to the gut microbiome, where oxygen levels are minimal. The presence of Akkermansia muciniphila in the gut has been associated with various health benefits, including modulation of host metabolism and immune responses, although specific interactions and implications for strain EB-AMDK-17 remain to be elucidated. Understanding the functional capabilities and ecological roles of this strain can provide insights into its potential contributions to gut homeostasis and overall host health.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainEB-AMDK-17

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila str. EB-AMDK-17
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain EB-AMDK-17 chromosome, complete

Gene Summary

Adenine Count

618960 bp

Thymine Count

619260 bp

Guanine Count

768603 bp

Cytosine Count

763323 bp

Genome Length

2770146 bp

Protein-coding Genes

2296 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pep-cterm sorting domain-containing proteinC1O54_RS04320Not AvailableNegative1016677 - 101733022432.3
o-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family proteinC1O54_RS04325Not AvailableNegative1017718 - 101900747269.2
radical sam proteinC1O54_RS04330Not AvailableNegative1019268 - 102051545495.1
radical sam proteinC1O54_RS04335Not AvailableNegative1020508 - 102156939541.6
hypothetical proteinC1O54_RS04340Not AvailableNegative1021641 - 102245929552.8
exosortase system-associated protein, tigr04073 familyC1O54_RS04345Not AvailableNegative1022600 - 102303415924.0
nad(p)h-dependent glycerol-3-phosphate dehydrogenaseC1O54_RS04350Not AvailableNegative1023092 - 102410236332.2
glycerol-3-phosphate 1-o-acyltransferase plsyC1O54_RS04355Not AvailableNegative1024104 - 102474823225.9
pp2c family protein-serine/threonine phosphataseC1O54_RS04360Not AvailableNegative1025001 - 102578628508.6
lysine--trna ligaseC1O54_RS04365Not AvailableNegative1025804 - 102728555803.9

Displaying genes 871 – 880 of 2361 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total