Akkermansia muciniphila str. EB-AMDK-17

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain EB-AMDK-17 is a Gram-negative, anaerobic coccus that primarily exists in pairs or as single cells. This strain thrives optimally at a temperature of 37.0°C, suggesting its adaptation to a host-associated environment, likely reflecting its role in the gastrointestinal tract of various organisms. As a member of the Akkermansia genus, this strain is known to be involved in the metabolism of mucin, a glycoprotein component of mucus, which indicates a specialized niche within the mucosal layer of the gut. The ability to thrive in anaerobic conditions further emphasizes its adaptation to the gut microbiome, where oxygen levels are minimal. The presence of Akkermansia muciniphila in the gut has been associated with various health benefits, including modulation of host metabolism and immune responses, although specific interactions and implications for strain EB-AMDK-17 remain to be elucidated. Understanding the functional capabilities and ecological roles of this strain can provide insights into its potential contributions to gut homeostasis and overall host health.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainEB-AMDK-17

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila str. EB-AMDK-17
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain EB-AMDK-17 chromosome, complete

Gene Summary

Adenine Count

618960 bp

Thymine Count

619260 bp

Guanine Count

768603 bp

Cytosine Count

763323 bp

Genome Length

2770146 bp

Protein-coding Genes

2296 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lps export abc transporter atp-binding proteinC1O54_RS03765Not AvailablePositive886993 - 88773927746.8
haloacid dehalogenase-like hydrolaseC1O54_RS03770Not AvailablePositive887760 - 88864433101.2
udp-n-acetylmuramate:l-alanyl-gamma-d-glutamyl- meso-diaminopimelate ligaseC1O54_RS03775Not AvailablePositive888670 - 89005250439.4
ompa family proteinC1O54_RS11950Not AvailablePositive890077 - 89139648062.0
atp-dependent helicaseC1O54_RS03785Not AvailablePositive891479 - 89348876065.6
autotransporter outer membrane beta-barrel domain-containing proteinC1O54_RS03790Not AvailablePositive894472 - 897627108553.0
duf4124 domain-containing proteinC1O54_RS03795Not AvailablePositive897940 - 8981436969.08
pep-cterm sorting domain-containing proteinC1O54_RS03800Not AvailablePositive898270 - 89868314529.3
asparagine--trna ligaseC1O54_RS03805Not AvailableNegative898849 - 90021651369.1
c39 family peptidaseC1O54_RS03810Not AvailableNegative900325 - 90160547378.0

Displaying genes 761 – 770 of 2361 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total