Akkermansia muciniphila str. EB-AMDK-17

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain EB-AMDK-17 is a Gram-negative, anaerobic coccus that primarily exists in pairs or as single cells. This strain thrives optimally at a temperature of 37.0°C, suggesting its adaptation to a host-associated environment, likely reflecting its role in the gastrointestinal tract of various organisms. As a member of the Akkermansia genus, this strain is known to be involved in the metabolism of mucin, a glycoprotein component of mucus, which indicates a specialized niche within the mucosal layer of the gut. The ability to thrive in anaerobic conditions further emphasizes its adaptation to the gut microbiome, where oxygen levels are minimal. The presence of Akkermansia muciniphila in the gut has been associated with various health benefits, including modulation of host metabolism and immune responses, although specific interactions and implications for strain EB-AMDK-17 remain to be elucidated. Understanding the functional capabilities and ecological roles of this strain can provide insights into its potential contributions to gut homeostasis and overall host health.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainEB-AMDK-17

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila str. EB-AMDK-17
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain EB-AMDK-17 chromosome, complete

Gene Summary

Adenine Count

618960 bp

Thymine Count

619260 bp

Guanine Count

768603 bp

Cytosine Count

763323 bp

Genome Length

2770146 bp

Protein-coding Genes

2296 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
udp-n-acetylmuramate--l-alanine ligaseC1O54_RS03665Not AvailablePositive865339 - 86763683102.7
d-alanine--d-alanine ligaseC1O54_RS03670Not AvailablePositive867659 - 86859433288.0
cell division protein ftsq/divibC1O54_RS03675Not AvailablePositive868642 - 86959236108.8
recombinase recaC1O54_RS03680Not AvailablePositive869818 - 87085837290.8
n-acetylmuramoyl-l-alanine amidase family proteinC1O54_RS03685Not AvailablePositive871018 - 87203737876.9
lipoyl(octanoyl) transferase lipbC1O54_RS03690Not AvailablePositive872073 - 87271123812.8
3-isopropylmalate dehydratase large subunitC1O54_RS03695Not AvailablePositive872914 - 87432650549.6
3-isopropylmalate dehydratase small subunitC1O54_RS03700Not AvailablePositive874346 - 87495421947.2
hypothetical proteinC1O54_RS03705Not AvailablePositive874999 - 87612042821.1
s1c family serine proteaseC1O54_RS03710Not AvailablePositive876162 - 87773657467.3

Displaying genes 741 – 750 of 2361 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total