Akkermansia muciniphila str. EB-AMDK-17

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila strain EB-AMDK-17 is a Gram-negative, anaerobic coccus that primarily exists in pairs or as single cells. This strain thrives optimally at a temperature of 37.0°C, suggesting its adaptation to a host-associated environment, likely reflecting its role in the gastrointestinal tract of various organisms. As a member of the Akkermansia genus, this strain is known to be involved in the metabolism of mucin, a glycoprotein component of mucus, which indicates a specialized niche within the mucosal layer of the gut. The ability to thrive in anaerobic conditions further emphasizes its adaptation to the gut microbiome, where oxygen levels are minimal. The presence of Akkermansia muciniphila in the gut has been associated with various health benefits, including modulation of host metabolism and immune responses, although specific interactions and implications for strain EB-AMDK-17 remain to be elucidated. Understanding the functional capabilities and ecological roles of this strain can provide insights into its potential contributions to gut homeostasis and overall host health.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainEB-AMDK-17

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila str. EB-AMDK-17
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain EB-AMDK-17 chromosome, complete

Gene Summary

Adenine Count

618960 bp

Thymine Count

619260 bp

Guanine Count

768603 bp

Cytosine Count

763323 bp

Genome Length

2770146 bp

Protein-coding Genes

2296 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
16s rrna (cytosine(1402)-n(4))-methyltransferase rsmhC1O54_RS03615Not AvailablePositive852848 - 85441056478.2
hypothetical proteinC1O54_RS03620Not AvailablePositive854433 - 85477712857.4
peptidoglycan d,d-transpeptidase ftsi family proteinC1O54_RS03625Not AvailablePositive854794 - 85689376663.0
udp-n-acetylmuramoyl-l-alanyl-d-glutamate--2, 6-diaminopimelate ligaseC1O54_RS03630Not AvailablePositive856901 - 85840655117.3
udp-n-acetylmuramoyl-tripeptide--d-alanyl-d- alanine ligaseC1O54_RS03635Not AvailablePositive858429 - 85980248786.5
phospho-n-acetylmuramoyl-pentapeptide- transferaseC1O54_RS03640Not AvailablePositive859808 - 86091139241.0
udp-n-acetylmuramoyl-l-alanine--d-glutamate ligaseC1O54_RS03645Not AvailablePositive860924 - 86223447144.4
lysm peptidoglycan-binding domain-containing proteinC1O54_RS03650Not AvailablePositive862258 - 86305829363.7
ftsw/roda/spove family cell cycle proteinC1O54_RS03655Not AvailablePositive863083 - 86422541751.0
undecaprenyldiphospho-muramoylpentapeptide beta-n-acetylglucosaminyltransferaseC1O54_RS03660Not AvailablePositive864222 - 86534640407.8

Displaying genes 731 – 740 of 2361 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total