Akkermansia muciniphila str. EB-AMDK-15

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila str. EB-AMDK-15 is a Gram-negative, anaerobic cocci that typically exists in host-associated environments, thriving optimally at a temperature of 37.0°C. This strain is characterized by its unique cellular arrangement, where cells predominantly form pairs and can also be observed as singles. As a member of the Akkermansia genus, this strain is known to inhabit mucosal surfaces, suggesting a specialized role in the microbiota of its host. Its anaerobic nature indicates an adaptation to environments devoid of oxygen, which is common in the gastrointestinal tract where it can contribute to host health. The ability to persist in such ecological niches may be linked to its metabolic capabilities, particularly in utilizing mucin as a carbon source, thus potentially influencing gut health and homeostasis. The presence of Akkermansia muciniphila, including strain EB-AMDK-15, in the gut microbiome is emerging as a significant aspect of microbial ecology, with implications for gut barrier function and overall metabolic health. Understanding its specific traits and behaviors could provide insights into the complex interactions within the gastrointestinal microbiota and their impact on host physiology.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainEB-AMDK-15

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila str. EB-AMDK-15
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain EB-AMDK-15 chromosome, complete

Gene Summary

Adenine Count

618989 bp

Thymine Count

619239 bp

Guanine Count

768574 bp

Cytosine Count

763296 bp

Genome Length

2770098 bp

Protein-coding Genes

2326 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
smp-30/gluconolactonase/lre family proteinC1O50_RS00385Not AvailablePositive95446 - 9636033398.0
gatb/yqey domain-containing proteinC1O50_RS00390Not AvailablePositive96479 - 9693416558.3
2-c-methyl-d-erythritol 4-phosphate cytidylyltransferaseC1O50_RS00395Not AvailablePositive96931 - 9762625756.8
nad-dependent epimerase/dehydratase family proteinC1O50_RS00400Not AvailablePositive97623 - 9847730803.1
tryptophan--trna ligaseC1O50_RS00405Not AvailablePositive98668 - 9963335864.9
universal stress proteinC1O50_RS00410Not AvailablePositive99722 - 10019217157.7
tigr00282 family metallophosphoesteraseC1O50_RS00415Not AvailablePositive100226 - 10102928977.0
trna cyclic n6-threonylcarbamoyladenosine(37) synthase tcdaC1O50_RS00420Not AvailablePositive101354 - 10214828236.1
hypothetical proteinC1O50_RS00425Not AvailablePositive102145 - 10266019582.4
Trna-leuNot AvailableNot AvailablePositive102764 - 102849Not Available

Displaying genes 81 – 90 of 2391 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total