Akkermansia muciniphila str. EB-AMDK-15

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Verrucomicrobiota

Class

Verrucomicrobiia

Order

Verrucomicrobiales

Family

Akkermansiaceae

Genus

Akkermansia

Description

Akkermansia muciniphila str. EB-AMDK-15 is a Gram-negative, anaerobic cocci that typically exists in host-associated environments, thriving optimally at a temperature of 37.0°C. This strain is characterized by its unique cellular arrangement, where cells predominantly form pairs and can also be observed as singles. As a member of the Akkermansia genus, this strain is known to inhabit mucosal surfaces, suggesting a specialized role in the microbiota of its host. Its anaerobic nature indicates an adaptation to environments devoid of oxygen, which is common in the gastrointestinal tract where it can contribute to host health. The ability to persist in such ecological niches may be linked to its metabolic capabilities, particularly in utilizing mucin as a carbon source, thus potentially influencing gut health and homeostasis. The presence of Akkermansia muciniphila, including strain EB-AMDK-15, in the gut microbiome is emerging as a significant aspect of microbial ecology, with implications for gut barrier function and overall metabolic health. Understanding its specific traits and behaviors could provide insights into the complex interactions within the gastrointestinal microbiota and their impact on host physiology.

Taxonomy

KingdomPseudomonadati
PhylumVerrucomicrobiota
ClassVerrucomicrobiia
OrderVerrucomicrobiales
FamilyAkkermansiaceae
GenusAkkermansia
SpeciesAkkermansia muciniphila
StrainEB-AMDK-15

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Akkermansia muciniphila str. EB-AMDK-15
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementPairs - Singles
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Akkermansia muciniphila strain EB-AMDK-15 chromosome, complete

Gene Summary

Adenine Count

618989 bp

Thymine Count

619239 bp

Guanine Count

768574 bp

Cytosine Count

763296 bp

Genome Length

2770098 bp

Protein-coding Genes

2326 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetyl-coa hydrolase/transferase family proteinC1O50_RS01265Not AvailablePositive304702 - 30619854050.7
hypothetical proteinC1O50_RS01270Not AvailablePositive306317 - 30701825143.7
hypothetical proteinC1O50_RS01275Not AvailablePositive307077 - 3073259147.84
glucose-1-phosphate thymidylyltransferase rfbaC1O50_RS01280Not AvailableNegative307292 - 30815532105.7
dtdp-glucose 4,6-dehydrataseC1O50_RS01285Not AvailableNegative308165 - 30921739636.7
6-phosphofructokinaseC1O50_RS01290Not AvailableNegative309349 - 31031135311.1
uracil-dna glycosylase family proteinC1O50_RS01295Not AvailablePositive310422 - 31115326704.1
asp-trna(asn)/glu-trna(gln) amidotransferase subunit gatbC1O50_RS01300Not AvailablePositive311518 - 31298454465.3
thiamine pyrophosphate-binding proteinC1O50_RS01305Not AvailableNegative313039 - 31476963166.2
hypothetical proteinC1O50_RS01310Not AvailableNegative314940 - 31568925603.9

Displaying genes 261 – 270 of 2391 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Food allergyCausesPMC11210198
Thinning of the jejunum mucus layerCausesPMC7527075

Displaying health effects 1 – 2 of 2 in total