Helicobacter hepaticus ATCC 51449

Gram-negativeSpirillaMotileAerobe

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter hepaticus is responsible for chronic hepatitis and liver cancer in mice. It has also been linked to inflammatory bowel disease in immunocompromised mice. H.hepaticus does not colonize the stomach but inhabits the lower bowel. (HAMAP: HELHP)

Taxonomy

Kingdom	Pseudomonadati
Phylum	Campylobacterota
Class	Epsilonproteobacteria
Order	Campylobacterales
Family	Helicobacteraceae
Genus	Helicobacter
Species	Helicobacter hepaticus
Strain	ATCC 51449

Profile

Physiology
Gram staining properties	Negative
Shape	Spirilla
Mobility	Yes
Flagellar presence	Yes
Number of membranes	2

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Aerobe
Optimal temperature	37
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Not Available
Host(s)	Not Available
Cell arrangement	Not Available
Sporulation	Not Available
Energy source	Not Available
Pathogenicity	No

Genome Summary

Helicobacter hepaticus ATCC 51449, complete sequence.

NC_004917.1

Gene Summary

Adenine Count

579214 bp

Thymine Count

573476 bp

Guanine Count

318316 bp

Cytosine Count

328140 bp

Genome Length

1799146 bp

Protein-coding Genes

1797 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
hypothetical protein	HH_RS03460	Not Available	Positive	677368 - 678453	42068.8
ribonuclease hi	HH_RS03465	Not Available	Positive	678428 - 678868	16224.4
ribonuclease iii	HH_RS03470	Not Available	Positive	678861 - 679583	27284.8
chorismate synthase	HH_RS03475	Not Available	Positive	679580 - 680656	38837.6
asp-trna(asn)/glu-trna(gln) amidotransferase subunit gata	HH_RS03480	Not Available	Positive	680733 - 682076	48778.4
imp dehydrogenase	HH_RS03485	Not Available	Positive	682096 - 683541	52037.1
exodeoxyribonuclease vii small subunit	HH_RS03490	Not Available	Positive	683552 - 683800	9596.31
flagellar biosynthetic protein flir	HH_RS03495	Not Available	Positive	683806 - 684582	28386.9
phospholipase d-like domain-containing protein	HH_RS03500	Not Available	Negative	684584 - 685150	21574.5
hypothetical protein	HH_RS03505	Not Available	Positive	685229 - 687043	67025.3

Displaying genes 731 – 740 of 1853 in total

Pathways

1200 pathways

2,3-Dihydroxybenzoate Biosynthesis

Biosynthesis of Siderophore Group Nonribosomal Peptides

Lysine Biosynthesis

Proline Metabolism

Palmitate Biosynthesis

Fatty Acid Elongation (Saturated)

tRNA Charging

Glycine Biosynthesis

Show All 1200 Pathways

Metabolite ID	Metabolite name	CAS number	Average mass Monoisotopic mass
BASm0000237	(R)-4'-phosphopantothenateC9H18NO8P	Not available	Average299.2149Da Monoisotopic299.0770031Da
BASm0000251	2-dehydropantoateC6H9O4	Not available	Average145.1333Da Monoisotopic145.050083776Da
BASm0000260	3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5	Not available	Average405.556Da Monoisotopic405.264647871Da
BASm0000377	(S)-malateC4H4O5	Not available	Average132.0716Da Monoisotopic132.005873238Da
BASm0000387	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6	Not available	Average455.432Da Monoisotopic455.1564286Da
BASm0000592	(S)-1-phenylethanolC8H10O	Not available	Average122.1644Da Monoisotopic122.0731649Da
BASm0000989	GlycerolC3H8O3	`56-81-5`	Average92.0938Da Monoisotopic92.04734412Da
BASm0001225	dodecanoateC12H23O2	Not available	Average199.3098Da Monoisotopic199.169805Da
BASm0001244	2-succinylbenzoateC11H8O5	`27415-09-04`	Average220.181Da Monoisotopic220.038270517Da
BASm0001462	ubiquinone-0C9H10O4	`605-94-7`	Average182.1733Da Monoisotopic182.057908808Da