Helicobacter hepaticus ATCC 51449

Gram-negativeSpirillaMotileAerobe

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter hepaticus is responsible for chronic hepatitis and liver cancer in mice. It has also been linked to inflammatory bowel disease in immunocompromised mice. H.hepaticus does not colonize the stomach but inhabits the lower bowel. (HAMAP: HELHP)

Taxonomy

Kingdom	Pseudomonadati
Phylum	Campylobacterota
Class	Epsilonproteobacteria
Order	Campylobacterales
Family	Helicobacteraceae
Genus	Helicobacter
Species	Helicobacter hepaticus
Strain	ATCC 51449

Profile

Physiology
Gram staining properties	Negative
Shape	Spirilla
Mobility	Yes
Flagellar presence	Yes
Number of membranes	2

Image source: Wikipedia/Wikimedia

Ecology, Host, and Life Cycle
Oxygen requirements	Aerobe
Optimal temperature	37
Temperature range	Mesophilic
Habitat	HostAssociated
Biotic relationship	Not Available
Host(s)	Not Available
Cell arrangement	Not Available
Sporulation	Not Available
Energy source	Not Available
Pathogenicity	No

Genome Summary

Helicobacter hepaticus ATCC 51449, complete sequence.

NC_004917.1

Gene Summary

Adenine Count

579214 bp

Thymine Count

573476 bp

Guanine Count

318316 bp

Cytosine Count

328140 bp

Genome Length

1799146 bp

Protein-coding Genes

1797 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

Genes

Name	Locus Tag	UniProt ID	Strand Orientation	Gene Start/End	Protein Molecular Weight
ribonucleotide-diphosphate reductase subunit beta	HH_RS03010	Not Available	Negative	584030 - 585079	40420.1
Trna-leu	Not Available	Not Available	Positive	585214 - 585298	Not Available
1-deoxy-d-xylulose-5-phosphate synthase	HH_RS03020	Not Available	Negative	585378 - 587267	69415.8
flagellar assembly protein flih	HH_RS03025	Not Available	Negative	587293 - 588126	31029.9
flagellar motor switch protein flig	HH_RS03030	Not Available	Negative	588113 - 589144	38098.0
flagellar basal-body ms-ring/collar protein flif	HH_RS03035	Not Available	Negative	589160 - 590872	64920.9
histidinol-phosphate transaminase	HH_RS03040	Not Available	Negative	590882 - 591994	41705.2
phosphomannomutase/phosphoglucomutase	HH_RS03045	Not Available	Positive	592187 - 593635	54216.1
dihydroorotase	HH_RS03050	Not Available	Positive	593645 - 594676	38497.1
radical sam family heme chaperone hemw	HH_RS03055	Not Available	Negative	594693 - 595808	42395.4

Displaying genes 641 – 650 of 1853 in total

Pathways

1200 pathways

2,3-Dihydroxybenzoate Biosynthesis

Biosynthesis of Siderophore Group Nonribosomal Peptides

Lysine Biosynthesis

Proline Metabolism

Palmitate Biosynthesis

Fatty Acid Elongation (Saturated)

tRNA Charging

Glycine Biosynthesis

Show All 1200 Pathways

Metabolite ID	Metabolite name	CAS number	Average mass Monoisotopic mass
BASm0000237	(R)-4'-phosphopantothenateC9H18NO8P	Not available	Average299.2149Da Monoisotopic299.0770031Da
BASm0000251	2-dehydropantoateC6H9O4	Not available	Average145.1333Da Monoisotopic145.050083776Da
BASm0000260	3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5	Not available	Average405.556Da Monoisotopic405.264647871Da
BASm0000377	(S)-malateC4H4O5	Not available	Average132.0716Da Monoisotopic132.005873238Da
BASm0000387	(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6	Not available	Average455.432Da Monoisotopic455.1564286Da
BASm0000592	(S)-1-phenylethanolC8H10O	Not available	Average122.1644Da Monoisotopic122.0731649Da
BASm0000989	GlycerolC3H8O3	`56-81-5`	Average92.0938Da Monoisotopic92.04734412Da
BASm0001225	dodecanoateC12H23O2	Not available	Average199.3098Da Monoisotopic199.169805Da
BASm0001244	2-succinylbenzoateC11H8O5	`27415-09-04`	Average220.181Da Monoisotopic220.038270517Da
BASm0001462	ubiquinone-0C9H10O4	`605-94-7`	Average182.1733Da Monoisotopic182.057908808Da