Roseomonas mucosa

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Alphaproteobacteria

Order

Acetobacterales

Family

Roseomonadaceae

Genus

Roseomonas

Description

Roseomonas mucosa is a Gram-negative, coccoid-shaped bacterium categorized as a mesophile, thriving optimally at moderate temperatures, and is classified as a chemoheterotroph, utilizing organic compounds for energy and growth. This microbe is part of the diverse human microbiota, found in various body sites, including the skin, respiratory tract, and gastrointestinal tract. It is considered a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments, which contributes to its adaptability in different niches within the human body. The Gram-negative nature of Roseomonas mucosa is characterized by its thin peptidoglycan layer and outer membrane containing lipopolysaccharides, which can influence its interaction with the immune system. The coccoid shape allows for efficient colonization and establishment in the human microbiome. Being mesophilic, it thrives in the moderate temperature ranges typical of human body sites, making it well-suited for survival in such environments. As a chemoheterotroph, Roseomonas mucosa relies on organic nutrients derived from the host or surrounding environments, highlighting its role in nutrient cycling within the microbiome. Its facultative anaerobic metabolism allows it to adapt to varying oxygen levels, enabling it to persist in different tissues and conditions. Beyond its role in the human microbiome, Roseomonas mucosa has attracted interest in clinical microbiology due to its potential association with opportunistic infections, particularly in immunocompromised individuals. Recent studies have suggested a possible link between this microbe and skin conditions, underscoring the need for further research to understand its pathogenic potential and environmental adaptability.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassAlphaproteobacteria
OrderAcetobacterales
FamilyRoseomonadaceae
GenusRoseomonas
SpeciesRoseomonas mucosa
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Roseomonas mucosa
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitataquatic environments; healthy skin
Biotic relationshipNot Available
Host(s)Homo sapiens, Lasius niger
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Roseomonas mucosa strain NCTC13291 genome assembly, contig:

Gene Summary

Adenine Count

744834 bp

Thymine Count

739831 bp

Guanine Count

1757501 bp

Cytosine Count

1758403 bp

Genome Length

5000569 bp

Protein-coding Genes

4506 genes

Non-Coding Genes

105 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Is3 family transposaseNCTC13291_04484Not AvailableNegative4856251 - 485660712711.4
uncharacterised proteinNCTC13291_04485Not AvailableNegative4856633 - 485703114653.7
TransposaseNCTC13291_04486Not AvailablePositive4857085 - 485742913601.4
TransposaseNCTC13291_04487Not AvailableNegative4857432 - 485814228096.1
uncharacterised proteinNCTC13291_04488Not AvailablePositive4858285 - 485932538225.2
Serine-type dna invertase finNCTC13291_04489Not AvailableNegative4859471 - 486006121606.2
post-segregation antitoxin (ccd killing mechanism protein) encoded by the f plasmidNCTC13291_04490Not AvailablePositive4860261 - 48605099096.76
ccdb proteinNCTC13291_04491Not AvailablePositive4860509 - 486081110928.6
Dna binding protein hu-betaNCTC13291_04492Not AvailablePositive4860993 - 48612599314.35
Transposase of is904hNCTC13291_04493Not AvailableNegative4861270 - 486234639865.2

Displaying genes 21 – 30 of 4611 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0034631TG(18:4(6Z,9Z,12Z,15Z)/18:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z))C59H94O6Chemical structure of TG(18:4(6Z,9Z,12Z,15Z)/18:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z))NULL
Average899.395Da
Monoisotopic898.705040747Da
BASm0034653Starch, Structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]})C66H112O56Chemical structure of Starch, Structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]})NULL
Average1801.566Da
Monoisotopic1800.591622326Da
BASm0039640Streptococcus constellatusNot available7296-56-2Not available

Displaying 1–4 of 4 metabolites

Health Effects

Health ConditionRelationReference
Peritoneal dialysis (pd)-related peritonitisCausesPMC11414375
Infectious spondylitisCausesPMC4607774
BacteremiaCausesPMC4607774
InfectionsCausesPMC5391405
Bacterial peritonitisCausesPMC5411560
BacteremiaCausesPMC6249398

Displaying health effects 1 – 6 of 6 in total