Ehrlichia chaffeensis str. Arkansas

Gram-negativeRodNon-motile

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Alphaproteobacteria

Order

Rickettsiales

Family

Anaplasmataceae

Genus

Ehrlichia

Description

Ehrlichia chaffeensis (strain Arkansas) is an intracellular vector-borne pathogen that causes human ehrlichiosis. It depends on hematophagous ticks as a vector and wild mammals as a reservoir host. It has been most commonly identified in the Lone Star tick (Amblyomma americanum), with white-tailed deer considered to be the major reservoir. E. chaffeensis is the causative agent of human monocytic ehrlichiosis (HME), a disease that was discovered in 1986. It is a systemic disease that is indistinguishable from human granulocytic ehrlichiosis (HGA) caused by Anaplasma phagocytophilum. It replicates in monocytes/macrophages. The genome of E. chaffeensis is made up of a singular chromosome. Despite the limited ability of Rickettsiales to synthesize amino acids, E.chaffeensis seems to be able to synthesize arginine and lysine. (EBI Integr8)

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassAlphaproteobacteria
OrderRickettsiales
FamilyAnaplasmataceae
GenusEhrlichia
SpeciesEhrlichia chaffeensis
StrainArkansas

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Ehrlichia chaffeensis str. Arkansas
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityYes

Genome Summary

Ehrlichia chaffeensis str. Arkansas, complete sequence.

Gene Summary

Adenine Count

413077 bp

Thymine Count

409112 bp

Guanine Count

180030 bp

Cytosine Count

174029 bp

Genome Length

1176248 bp

Protein-coding Genes

931 genes

Non-Coding Genes

43 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
virb4 family type iv secretion/conjugal transfer atpaseECH_RS02060Q9R2W4Positive481344 - 48374690723.2
type iv secretion system proteinECH_RS02065Q1RH19Positive483786 - 48626690561.8
type iv secretion system proteinECH_RS02070Q9ZE41Positive486464 - 489232103951.0
type iv secretion system proteinECH_RS02075Q9ZE40Positive489236 - 493642159113.0
type iv secretion system proteinECH_RS02080Q4UNB4Positive493681 - 501957302963.0
duf2460 domain-containing proteinECH_RS02085Not AvailableNegative502109 - 50270823522.9
dutp diphosphataseECH_RS02090Q3YRU2Negative502914 - 50335715926.2
4-hydroxy-3-methylbut-2-enyl diphosphate reductaseECH_RS02095Q5FFL5Negative503528 - 50448735848.5
glutamine-hydrolyzing carbamoyl-phosphate synthase small subunitECH_RS02100P57245Negative505048 - 50616341458.5
ribosome biogenesis gtpase derECH_RS02105A5EI59Positive506393 - 50772150160.4

Displaying genes 421 – 430 of 974 in total

Metabolites

1616 records
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Result columns

Structure search compares stored SMILES, InChI, and InChIKey text. Exact mass must match the stored database value.

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Metabolite IDMetabolite nameStructureCAS number
Average massMonoisotopic mass
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0001717fumarateC4H2O4Chemical structure of fumarateNot available
Average114.0563Da
Monoisotopic113.9953086Da

Displaying 1–10 of 1616 metabolites

Health Effects

No health effects information available for this bacterium.