Corynebacterium simulans str. PES1

facultative aerobe/anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Corynebacterium simulans str. PES1 is a Gram-positive bacterium characterized by its facultative anaerobic metabolism and inability to form spores. This strain thrives optimally at a temperature of 37.0°C, aligning with the typical conditions of mammalian hosts. As a facultative aerobe/anaerobe, C. simulans str. PES1 can adapt to varying oxygen levels, allowing it to survive in diverse environments, including both aerobic and microaerophilic conditions. The inability to form spores suggests that C. simulans str. PES1 may be less resilient to extreme environmental stresses compared to spore-forming bacteria, which utilize sporulation as a survival strategy. However, its Gram-positive nature indicates a robust cell wall structure, which may confer some degree of protection against environmental challenges. This strain's optimal growth temperature of 37.0°C suggests a potential association with warm-blooded hosts, where it may play a role in the microbiome or in specific biochemical processes. The adaptability of C. simulans str. PES1 to different oxygen conditions may facilitate its survival in complex ecosystems, potentially influencing nutrient cycling or microbial community dynamics. Understanding the physiological traits of this strain could provide insights into its ecological roles and interactions within microbial communities.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium simulans
StrainPES1

Profile

Physiology
Gram staining propertiesGram-positive
ShapeNot Available
Mobilitynon-motile
Flagellar presenceNot Available
Number of membranesNot Available
Image of Corynebacterium simulans str. PES1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsfacultative aerobe/anaerobe
Optimal temperature37
Temperature rangemesophilic
Habitatskin
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
Sporulationnon-spore-forming
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Corynebacterium simulans strain PES1 chromosome, complete genome.

Gene Summary

Adenine Count

563408 bp

Thymine Count

558941 bp

Guanine Count

805062 bp

Cytosine Count

810560 bp

Genome Length

2737971 bp

Protein-coding Genes

2485 genes

Non-Coding Genes

81 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
choice-of-anchor m domain-containing proteinWM42_RS00995Not AvailablePositive212634 - 21356932992.4
anchored repeat-type abc transporter atp-binding subunitWM42_RS01000Not AvailablePositive213553 - 21429326350.8
anchored repeat-type abc transporter permease subunitWM42_RS01005Not AvailablePositive214290 - 21515629696.1
choice-of-anchor m domain-containing proteinWM42_RS01010Not AvailablePositive215172 - 21652748613.0
phb depolymerase family esteraseWM42_RS01015Not AvailableNegative216528 - 21767641679.2
isochorismate synthase menfWM42_RS01020Not AvailablePositive217766 - 21886939156.3
fumarylacetoacetate hydrolase family proteinWM42_RS01025Not AvailableNegative218937 - 21974629339.2
3-isopropylmalate dehydrogenaseWM42_RS01030Not AvailableNegative219820 - 22083635835.6
phosphoglycerate dehydrogenaseWM42_RS01035Not AvailableNegative220924 - 22251054938.9
hypothetical proteinWM42_RS01040Not AvailableNegative222577 - 22353334487.2

Displaying genes 221 – 230 of 2566 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

166 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm0000403(S)-acetoinC4H8O2Chemical structure of (S)-acetoinNot available
Average88.1051Da
Monoisotopic88.0524295Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0000848hexanoateC6H11O2Chemical structure of hexanoateNot available
Average115.1503Da
Monoisotopic115.075904596Da

Displaying 1–10 of 166 metabolites

Health Effects

Health ConditionRelationReference
Pulmonary infectionsCausesPMC7788810

Displaying health effects 1 – 1 of 1 in total