Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093

Helicobacter pylori NCTC 11637, also known by its other designations CCUG 17874, ATCC 43504, and JCM 12093, is a Gram-negative, microaerophilic bacterium characterized by its distinctive spirilla shape and arrangement as single cells. This organism thrives optimally at a temperature of 37.0°C, aligning with the typical physiological conditions of its host-associated habitat. H. pylori is predominantly found in the gastrointestinal tract of humans and is well recognized for its ability to colonize the gastric mucosa. The microaerophilic nature of this bacterium suggests that it requires a low concentration of oxygen for growth, which is consistent with the oxygen levels found in the stomach environment. The ability of H. pylori to maintain viability and activity in the acidic conditions of the stomach, alongside its spiral morphology, may contribute to its ability to penetrate the gastric mucus layer and adhere to epithelial cells. This unique adaptation highlights the complex interactions between H. pylori and its host, emphasizing its role in the microbial ecology of the human gut. Understanding these traits can provide insights into the physiological mechanisms underlying its resilience and potential implications for human health.