Helicobacter pylori J166

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori J166 is a Gram-negative bacterium characterized by its spirilla shape and arrangement in singles. This microbe is microaerophilic, thriving in environments with reduced oxygen levels, and has an optimal growth temperature of 37.0°C, which aligns with the typical conditions found within the human stomach. As a host-associated organism, H. pylori J166 occupies niche habitats within the gastric mucosa, where it is adapted to survive the harsh acidic conditions. The spiral morphology of H. pylori is believed to facilitate its motility through the viscous gastric mucus, allowing it to colonize the stomach lining effectively. The microaerophilic nature of this bacterium suggests a specialized adaptation to the low-oxygen microenvironments found in the human gastrointestinal tract. These traits may contribute to its persistence in the stomach and its potential role in influencing the host's gastric environment. Overall, the unique combination of its Gram-negative structure, microaerophilic lifestyle, and spirilla shape indicates a highly specialized organism that has evolved to exploit the specific conditions of its host-associated habitat. This adaptability highlights the intricate relationship between H. pylori J166 and its human host, emphasizing the importance of microbial adaptation in the context of gastrointestinal ecology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter pylori J166

Accession NumberNZ_CP007603.1

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1530 genes

Non-Coding Genes

45 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
transcription antitermination factor nusbEG65_RS00005Not Available-49 - 46515520.0
6,7-dimethyl-8-ribityllumazine synthaseEG65_RS00010Not Available-467 - 93716914.7
3-deoxy-8-phosphooctulonate synthaseEG65_RS00015Not Available-947 - 177730310.6
carbonic anhydraseEG65_RS00020Not Available-1764 - 242925795.8
orotidine-5'-phosphate decarboxylaseEG65_RS00025Not Available+2550 - 323325288.1
pantoate--beta-alanine ligaseEG65_RS00030Not Available+3234 - 406431023.9
Trna-gluNot AvailableNot Available+4078 - 4153Not Available
Trna-aspNot AvailableNot Available+4213 - 4289Not Available
Trna-valNot AvailableNot Available+4340 - 4415Not Available
Trna-gluNot AvailableNot Available+4458 - 4532Not Available

Displaying genes 1 – 10 of 1575 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

232 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000430hercynineC9H15N3O2Chemical structure of hercynineNot available
Average197.238Da
Monoisotopic197.1164267Da

Displaying 1–10 of 232 metabolites