Legionella pneumophila subsp. pneumophila

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila subsp. pneumophila is a Gram-negative, rod-shaped bacterium that typically exists as single cells. This microbe is classified as a chemoorganotroph, indicating that it derives energy through the oxidation of organic compounds. It is an aerobic organism, requiring oxygen for metabolic processes. L. pneumophila subsp. pneumophila is primarily associated with host environments, suggesting that it may thrive in specific ecological niches, such as within protozoa or other aquatic environments where it can evade predation and proliferate. The association with hosts is critical for its survival and propagation, highlighting the importance of understanding its life cycle and interaction with other microorganisms in its habitat. This bacterium is significant in the context of water systems, as it can colonize man-made water distribution systems, leading to potential health risks for humans. Its ability to persist in host-associated environments underscores the need for continued research into its ecological role and the mechanisms it employs to survive in diverse habitats. Understanding these traits not only provides insights into its biology but also informs strategies for controlling its presence in human-associated water systems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainsubsp. pneumophila

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila subsp. pneumophila
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Legionella pneumophila subsp. pneumophila strain L01C.1

Gene Summary

Adenine Count

1137790 bp

Thymine Count

1144379 bp

Guanine Count

710468 bp

Cytosine Count

706987 bp

Genome Length

3699624 bp

Protein-coding Genes

3253 genes

Non-Coding Genes

56 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
atp-dependent clp protease atp-binding subunit clpaD1H98_00005Not AvailableNegative160 - 243384311.7
atp-dependent clp protease adaptor clpsD1H98_00010Not AvailableNegative2459 - 279412722.4
nadp-dependent isocitrate dehydrogenaseD1H98_00015Not AvailableNegative3196 - 445245985.6
protein tyrosine phosphataseD1H98_00020Not AvailableNegative4562 - 526026302.9
pseudouridine synthaseD1H98_00025Not AvailablePositive5455 - 612326064.1
rod shape-determining protein mredD1H98_00030Not AvailableNegative6059 - 653818082.2
rod shape-determining protein mrecD1H98_00035Not AvailableNegative6535 - 744333460.6
rod shape-determining proteinD1H98_00040Not AvailableNegative7421 - 845836955.9
helix-hairpin-helix domain-containing proteinD1H98_00045Not AvailableNegative8654 - 897111774.5
m20/m25/m40 family metallo-hydrolaseD1H98_00050Not AvailableNegative9063 - 1047852499.1

Displaying genes 1 – 10 of 3309 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
LdCausesPMC7129662
Pontiac feverCausesPMC8023197
PneumoniaCausesPMC8023197
Legionnaires' diseaseCausesPMC2859405
Epidemic pneumoniaCausesPMC2859405

Displaying health effects 1 – 5 of 5 in total