Salmonella enterica subsp. enterica serovar Typhi

Gram-negativeSpirillaNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Salmonella

Description

Salmonella enterica subsp. enterica serovar Typhi is a Gram-negative bacterium characterized by its spirilla shape and the ability to exist as single cells or in chains. This microbe is a facultative anaerobe, enabling it to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37.0°C, which aligns with the human body temperature, reflecting its association with host environments. As a chemoorganotroph, S. enterica serovar Typhi derives energy from organic compounds, which is consistent with its habitat being primarily host-associated. The ecological niche of S. enterica serovar Typhi highlights its adaptation to life within a host, where it can exploit various organic substrates. This adaptation may contribute to its survival and persistence in the gastrointestinal tract of humans, where it can navigate complex microbial communities and host defenses. Understanding these traits can provide insights into the bacterium's role in human health and disease dynamics, particularly in relation to its transmission and survival strategies within host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusSalmonella
SpeciesSalmonella enterica
Strainsubsp. enterica serovar Typhi

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Salmonella enterica subsp. enterica serovar Typhi
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Pteropodidae
Cell arrangementChains - Singles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Salmonella enterica subsp. enterica serovar Typhi strain 5330

Gene Summary

Adenine Count

1162507 bp

Thymine Count

1167175 bp

Guanine Count

1269439 bp

Cytosine Count

1257253 bp

Genome Length

4856374 bp

Protein-coding Genes

4272 genes

Non-Coding Genes

451 genes

# of Chromosomes/Plasmids

7

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinE3D88_21925Not AvailablePositive4218495 - 421895317849.6
N-6 dna methylaseE3D88_21930Not AvailablePositive4219042 - 422099172356.0
hypothetical proteinE3D88_21935Not AvailablePositive4221063 - 422197135221.3
hypothetical proteinE3D88_21940Not AvailablePositive4222045 - 422294434750.2
duf3085 domain-containing proteinE3D88_21945Not AvailablePositive4222986 - 422334513710.6
hypothetical proteinE3D88_21950Not AvailableNegative4223445 - 42237149428.24
Dna polymeraseE3D88_21955Not AvailableNegative4223846 - 422512047828.6
hypothetical proteinE3D88_21960Not AvailableNegative4225120 - 42253207398.95
Hypothetical proteinE3D88_21965Not AvailablePositive4225340 - 422571714022.9
Ogr/delta-like zinc finger family proteinE3D88_21970Not AvailableNegative4225804 - 42260227952.43

Displaying genes 321 – 330 of 23283 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Acute cholecystitisCausesPMC10442058
Typhoid feverCausesPMC7845599
Typhoid feverCausesPMC10178548
Enteric feverCausesPMC10178548
Bloodstream infectionsCausesPMC10178548
TyphoidCausesPMC9967847

Displaying health effects 1 – 6 of 6 in total