Achromobacter xylosoxidans

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Burkholderiales

Family

Alcaligenaceae

Genus

Achromobacter

Description

Achromobacter xylosoxidans is a Gram-negative, rod-shaped microbe that thrives in mesophilic temperatures, categorized as a Chemoheterotroph, which relies on organic compounds for energy production, and can be found in various body sites, including the respiratory, urinary, and gastrointestinal tracts, in humans and animals, and is an Obligate Aerobe, requiring oxygen to survive. As a Gram-negative bacterium, Achromobacter xylosoxidans has a unique outer membrane composition, which plays a crucial role in its pathogenicity and antibiotic resistance. Its rod-shaped morphology allows it to adhere to and colonize various surfaces, including medical devices and host tissues. The mesophilic temperature preference of Achromobacter xylosoxidans enables it to thrive in a wide range of environments, from 20°C to 37°C, making it a versatile and opportunistic pathogen. As a Chemoheterotroph, Achromobacter xylosoxidans relies on the degradation of organic compounds, such as amino acids, carbohydrates, and fats, to produce energy. This energy production mechanism involves the breakdown of these compounds through various enzymatic reactions, resulting in the generation of ATP, which is then used to fuel its metabolic processes. Achromobacter xylosoxidans can be found in various body sites, including the respiratory, urinary, and gastrointestinal tracts, highlighting its ability to adapt to different environments and cause infections in various parts of the body. Achromobacter xylosoxidans is an Obligate Aerobe, requiring oxygen to survive and grow, which makes it well-suited to colonize areas with high oxygen levels, such as the lungs and skin. The microbe's ability to produce biofilms and form complex communities with other microorganisms allows it to persist in environments with limited nutrient availability, making it a challenging pathogen to eradicate. Achromobacter xylosoxidans has been implicated in various infections, including pneumonia, bacteremia, and urinary tract infections, particularly in individuals with compromised immune systems, and its presence has been detected in hospital environments, highlighting the need for strict infection control measures to prevent its spread.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderBurkholderiales
FamilyAlcaligenaceae
GenusAchromobacter
SpeciesAchromobacter xylosoxidans
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Achromobacter xylosoxidans
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Cicer arietinum, Erythrina brucei
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Achromobacter xylosoxidans strain NCTC10807 chromosome 1, complete

Gene Summary

Adenine Count

1111453 bp

Thymine Count

1111345 bp

Guanine Count

2288078 bp

Cytosine Count

2302306 bp

Genome Length

6813182 bp

Protein-coding Genes

6174 genes

Non-Coding Genes

128 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-aspartate oxidaseAT699_RS01310Q8XWM7Negative275032 - 27658854393.1
quinolinate synthase nadaAT699_RS01315Q0BCL4Negative276626 - 27776240286.3
mfs transporterAT699_RS01320P96675Negative277948 - 27918642400.7
lysr family transcriptional regulatorAT699_RS01325Not AvailablePositive279300 - 28024734904.3
n-carbamoyl-d-amino-acid hydrolaseAT699_RS01330Q44185Negative280266 - 28119834847.6
ornithine cyclodeaminaseAT699_RS01335Q88H32Positive281671 - 28273838182.8
ycjf family proteinAT699_RS01340Not AvailableNegative282769 - 28387838918.1
3-methyl-2-oxobutanoate hydroxymethyltransferaseAT699_RS01345Q2G6P1Negative283944 - 28472627394.2
lysr family transcriptional regulatorAT699_RS01350Q9I6Z9Negative284837 - 28575433522.3
sodium:solute symporterAT699_RS01355Q4L7L6Positive286005 - 28740549103.7

Displaying genes 351 – 360 of 17843 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

366 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000232(4S)-perillyl alcoholC10H16OChemical structure of (4S)-perillyl alcoholNot available
Average152.237Da
Monoisotopic152.1201151Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000288aminohydroquinoneC6H7NO2Chemical structure of aminohydroquinoneNot available
Average125.127Da
Monoisotopic125.0476785Da
BASm0000305tetrathionateO6S4Chemical structure of tetrathionateNot available
Average224.24Da
Monoisotopic223.8588696Da
BASm0000368(1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diolC7H10O2Chemical structure of (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diolNot available
Average126.155Da
Monoisotopic126.068079562Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da

Displaying 1–10 of 366 metabolites

Health Effects

Health ConditionRelationReference
Chronic mastoiditisCausesPMC12849298
PetrositisCausesPMC12849298
Septic arthritis of the temporomandibular jointCausesPMC12849298
PeritonitisCausesPMC3079607

Displaying health effects 1 – 4 of 4 in total