Lactobacillus crispatus

Gram-positiveRodNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Lactobacillaceae

Genus

Lactobacillus

Description

Lactobacillus crispatus is a type of gram-positive, rod-shaped bacterium that thrives in temperatures ranging from mesophilic to thermophilic, making it a mesophilic organism (temperature preference category). It is a chemoheterotroph, meaning it obtains its energy by breaking down organic compounds in its environment, such as sugars, amino acids, and fats (metabolism and energy source). This process involves fermentation, where the microbe converts glucose into lactate, generating energy through the reduction of pyruvate (energy production). Lactobacillus crispatus is gram-positive, meaning its cell wall contains a thick peptidoglycan layer, which gives it a positive reaction when tested with Gram stain. Its rod-shaped morphology is characteristic of many Lactobacillus species, allowing for efficient colonization and adhesion to host surfaces (shape). This microbe is found in various body sites, including the skin, mucous membranes, and gastrointestinal tract of humans and animals, playing a crucial role in maintaining the balance of the microbiome (all body sites in all possible species). Lactobacillus crispatus is a facultative anaerobe, capable of growing in the presence or absence of oxygen. While it can tolerate oxygen, it prefers microaerobic conditions, where oxygen levels are low to moderate (oxygen preference). This tolerance allows it to thrive in environments with varying oxygen levels. In addition to its role in maintaining the balance of the microbiome, Lactobacillus crispatus has been shown to produce antimicrobial substances, such as bacteriocins, which can help combat pathogenic microorganisms. It also exhibits probiotic properties, contributing to the prevention of certain diseases, including urinary tract infections and vaginal infections.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyLactobacillaceae
GenusLactobacillus
SpeciesLactobacillus crispatus
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Lactobacillus crispatus
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Gene Summary

Adenine Count

644065 bp

Thymine Count

649967 bp

Guanine Count

366193 bp

Cytosine Count

388504 bp

Genome Length

2048771 bp

Protein-coding Genes

1882 genes

Non-Coding Genes

70 genes

# of Chromosomes/Plasmids

10

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphoglyceromutaseAYQ00_00030Not AvailableNegative7381 - 807326491.2
hypothetical proteinAYQ00_00035Not AvailablePositive8229 - 898428286.0
5s ribosomal rnaNot AvailableNot AvailablePositive8549 - 8665Not Available
hypothetical proteinAYQ00_00040Not AvailablePositive9063 - 987529698.8
nad(p)-dependent oxidoreductaseAYQ00_00045Not AvailablePositive9883 - 1084835920.0
pyroglutamyl-peptidase iAYQ00_00050Not AvailablePositive10882 - 1152923341.3
potassium transporterAYQ00_00055Not AvailableNegative11574 - 1341267625.8
amidaseAYQ00_00060Not AvailableNegative13501 - 1458940906.5
n-acetylmuramidaseAYQ00_00065Not AvailableNegative14609 - 1583544904.0
transposaseAYQ00_00070Not AvailableNegative16325 - 165167078.87

Displaying genes 11 – 20 of 19664 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.