Corynebacterium propinquum

Gram-positiveRodFacultative anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Corynebacteriaceae

Genus

Corynebacterium

Description

Corynebacterium propinquum is a Gram-positive, rod-shaped bacterium classified under mesophiles, making it thrive optimally at moderate temperatures. It is a heterotrophic organism that primarily derives its energy from organic compounds, feeding on complex materials within its environment. C. propinquum is typically found in various body sites, including human skin, respiratory tract, and other mucosal surfaces. This microbe is classified as a facultative anaerobe, meaning it can grow in the presence or absence of oxygen, although it generally prefers oxygen-rich environments for optimal metabolic activity. The Gram-positive nature of C. propinquum indicates a thick peptidoglycan layer in its cell wall, which is characteristic of bacteria that can withstand harsh conditions. Its rod shape contributes to its ability to form characteristic palisades or Chinese letter arrangements when viewed under a microscope, a feature that can aid in its identification. As a mesophile, it grows best at temperatures around 30-37 degrees Celsius, making it well-suited for life on human hosts. In terms of its ecological role, C. propinquum participates in the normal microbiota of humans, playing a role in skin health and acting as a barrier against more harmful pathogens. While generally considered non-pathogenic, there are instances where it may be associated with opportunistic infections, particularly in immunocompromised individuals. Furthermore, studies suggest C. propinquum may produce bioactive compounds, potentially contributing to its role in maintaining microbial balance on human skin and mucosal surfaces. Its fascinating adaptability and interactions with human hosts highlight the intricate relationships that exist within our microbiome.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyCorynebacteriaceae
GenusCorynebacterium
SpeciesCorynebacterium propinquum
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Corynebacterium propinquum
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatnasopharynx; NP; upper respiratory tract
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

MAG: Corynebacterium propinquum isolate S2_005_003_R1_36

Gene Summary

Adenine Count

609989 bp

Thymine Count

606798 bp

Guanine Count

765617 bp

Cytosine Count

769685 bp

Genome Length

2752089 bp

Protein-coding Genes

2510 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
IntegraseDI558_11240Not AvailablePositive2440348 - 244130736717.8
Hypothetical proteinDI558_11245Not AvailableNegative2441588 - 244199215784.9
Hypothetical proteinDI558_11250Not AvailableNegative2441995 - 244239615340.1
LysineDI558_11255Not AvailableNegative2442594 - 244434365119.4
HolinDI558_11260Not AvailableNegative2444356 - 244464310429.8
Hypothetical proteinDI558_11265Not AvailableNegative2444699 - 24448425755.89
Hypothetical proteinDI558_11270Not AvailableNegative2444835 - 244517913193.5
Tail proteinDI558_11275Not AvailableNegative2445193 - 244623338179.3
Peptidoglycan hydrolaseDI558_11280Not AvailableNegative2446326 - 244826372936.7
AttlNot AvailableNot AvailablePositive2448282 - 2448293Not Available

Displaying genes 1 – 10 of 2578 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
Invasive diseaseCausesPMC12955418
Prosthetic valve endocarditisCausesPMC5116497
Native valve infective endocarditisCausesPMC5116497
Respiratory tract infectionsCausesPMC5116497
Acute nongonococcal urethritisCausesPMC5116497
Infective endocarditisCausesPMC5116497
Nosocomial infectionsCausesPMC5116497
Pulmonary infectionsCausesPMC7788810

Displaying health effects 1 – 8 of 8 in total