Ruminococcus bromii

Gram-positiveCocciAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Oscillospiraceae

Genus

Ruminococcus

Description

Ruminococcus bromii is a gram-positive, rod-shaped bacterium that belongs to the family Clostridiaceae. It is a thermophilic microbe, thriving in temperatures ranging from 37°C to 45°C, making it a common inhabitant of the human gut and rumen of ruminant animals. As a chemoheterotroph, R. bromii obtains its energy by breaking down complex carbohydrates and fiber into simpler molecules, which it uses to fuel its metabolic processes. R. bromii is a strict anaerobe, meaning it requires a complete absence of oxygen to survive and reproduce. In its natural environment, it thrives in the absence of oxygen, where it can utilize its anaerobic metabolism to generate energy. The bacterium produces energy through the fermentation of polysaccharides, releasing short-chain fatty acids, such as acetate, propionate, and butyrate, as byproducts. As a gut commensal, R. bromii is found in the intestines of humans and various animal species, where it plays a crucial role in the breakdown and utilization of dietary fiber. Its ability to ferment complex carbohydrates allows it to contribute to the production of short-chain fatty acids, which are essential for the health and function of the host gut. R. bromii is also a known inhabitant of the rumen of ruminant animals, such as cows and sheep, where it helps to break down and extract nutrients from plant-based feed. Its ability to ferment cellulose and other complex carbohydrates makes it an important component of the rumen microbiome. In addition to its role in the gut and rumen, R. bromii has been found to inhabit various other body sites, including the skin, respiratory tract, and genitourinary tract. Its ability to thrive in diverse environments and adapt to changing conditions makes it a resilient and widespread microbe. Despite its widespread distribution, R. bromii remains a relatively understudied microbe, with ongoing research aimed at understanding its metabolic processes and potential applications in fields such as agriculture and human health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyOscillospiraceae
GenusRuminococcus
SpeciesRuminococcus bromii
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Ruminococcus bromii
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatfeces; rectal mucosa
Biotic relationshipNot Available
Host(s)Homo sapiens, Bos taurus, Bos
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Ruminococcus bromii strain AF15-36 AF15-36.Scaf21, whole genome

Gene Summary

Adenine Count

651568 bp

Thymine Count

645550 bp

Guanine Count

447978 bp

Cytosine Count

438413 bp

Genome Length

2183559 bp

Protein-coding Genes

1932 genes

Non-Coding Genes

153 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinDWW40_06360Not AvailablePositive1317254 - 13174938729.69
hypothetical proteinDWW40_06365Not AvailablePositive1317497 - 13177399416.28
hypothetical proteinDWW40_06370Not AvailablePositive1317859 - 131821212902.6
Hypothetical proteinDWW40_06375Not AvailablePositive1318212 - 131938143607.7
Hypothetical proteinDWW40_06380Not AvailablePositive1319399 - 131994719791.3
Dna polymerase iDWW40_06385Not AvailablePositive1319944 - 132189072590.5
Virulence-associated e domain-containing proteinDWW40_06390Not AvailablePositive1321908 - 132430491806.9
Hypothetical proteinDWW40_06395Not AvailablePositive1324571 - 132487611643.3
Orf009DWW40_06400Not AvailablePositive1324836 - 132620652160.7
hypothetical proteinDWW40_06405Not AvailablePositive1326203 - 132655313792.4

Displaying genes 61 – 70 of 6226 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

151 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00011795-hydroxyisourateC5H4N4O4Chemical structure of 5-hydroxyisourateNot available
Average184.1097Da
Monoisotopic184.0232546Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da

Displaying 1–10 of 151 metabolites

Health Effects

No health effects information available for this bacterium.