Dorea formicigenerans

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Dorea

Description

Dorea formicigenerans is a Gram-positive, rod-shaped microbe that thrives in mesophilic temperatures, categorizing it as a chemoheterotroph, and can be found in various body sites of humans and animals, including the gastrointestinal tract, skin, and respiratory system. As an obligate anaerobe, Dorea formicigenerans requires the absence of oxygen to grow and survive, which is reflected in its optimal growth conditions. The Gram-positive characteristic of Dorea formicigenerans indicates that it has a thick peptidoglycan layer in its cell wall, providing it with a robust structure. Its rod shape allows it to maintain a large surface area, facilitating the exchange of nutrients and waste products. As a chemoheterotroph, Dorea formicigenerans relies on organic compounds for energy and carbon, which it obtains from its surroundings. This microbe can be found in a wide range of body sites, from the oral cavity to the gut, and even in the environment, such as in soil and water. The inability of Dorea formicigenerans to survive in the presence of oxygen makes it well adapted to environments with low oxygen levels, such as the human gut. Dorea formicigenerans plays a significant role in the fermentation of complex carbohydrates and production of short-chain fatty acids, which are essential for maintaining a healthy gut microbiome, and its unique metabolic capabilities allow it to contribute to the degradation of various organic compounds, making it a key player in the ecosystem.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusDorea
SpeciesDorea formicigenerans
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

3131 genes

Non-Coding Genes

157 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
integraseDXD10_00025Not AvailableNegative1695 - 278041796.3
uma2 family endonucleaseDXD10_00030Not AvailableNegative3001 - 354620901.9
hypothetical proteinDXD10_00035Not AvailableNegative3630 - 462839109.8
hypothetical proteinDXD10_00040Not AvailableNegative4691 - 512216826.2
lysm peptidoglycan-binding domain-containing proteinDXD10_00045Not AvailableNegative5407 - 579614709.3
transcriptional repressor lexaDXD10_00050Not AvailablePositive6089 - 670623208.2
ribosome silencing factorDXD10_00055Not AvailableNegative6807 - 716013385.7
hd domain-containing proteinDXD10_00060Not AvailableNegative7263 - 784422476.4
nicotinate-nucleotide adenylyltransferaseDXD10_00065Not AvailableNegative7816 - 844223984.9
ribosome assembly rna-binding protein yhbyDXD10_00070Not AvailableNegative8499 - 878910720.4

Displaying genes 51 – 60 of 11879 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.