Helicobacter heilmannii

curved/spiralmicroaerophile

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter heilmannii is a Gram-negative, curved or spiral-shaped microbe that thrives optimally at a temperature of 37.0°C and exhibits microaerophilic growth requirements. This bacterium is non-spore-forming, indicating that it does not produce spores as a means of survival under adverse conditions. Helicobacter heilmannii is closely associated with the gastric environment, where it likely interacts with the host's mucosal lining. Its microaerophilic nature suggests that it requires lower levels of oxygen for growth compared to atmospheric conditions, which aligns with its adaptation to the gastrointestinal tract where oxygen levels are typically reduced. The optimal growth temperature of 37.0°C reflects its adaptation to the warm-blooded host organisms, which may influence its distribution and interactions within various mammalian species. Understanding the traits of H. heilmannii provides insight into its potential role in the microbiome of the stomach and its possible interactions with other microbial species present in this niche. This microbe may contribute to the complex dynamics of gastric microbiota, influencing both host health and disease processes. Further investigation into its ecological role could enhance our understanding of microbial communities in the gastrointestinal tract and their impact on host physiology.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter heilmannii
StrainNo strain

Profile

Physiology
Gram staining propertiesGram-negative
Shapecurved/spiral
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Image of Helicobacter heilmannii
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsmicroaerophile
Optimal temperature37
Temperature rangemesophilic
HabitatNot Available
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Canis lupus familiaris
Cell arrangementNot Available
Sporulationnon-spore-forming
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Helicobacter heilmannii genome assembly Hheil, scaffold

Gene Summary

Adenine Count

423597 bp

Thymine Count

424810 bp

Guanine Count

386255 bp

Cytosine Count

386993 bp

Genome Length

1638988 bp

Protein-coding Genes

1710 genes

Non-Coding Genes

51 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphoserine aminotransferaseHHE01_08310O25436Positive8692 - 982841173.2
xanthine-guanine phosphoribosyltransferaseHHE01_08320Not AvailablePositive9828 - 1029217625.0
ribosomal protein s12p asp88 (e. coli) methylthiotransferaseHHE01_08330Q9ZLA9Positive10285 - 1158048077.9
hypothetical proteinHHE01_08340Not AvailableNegative11577 - 1288749410.9
thiol peroxidase, bcp-typeHHE01_08350Q9ZMU4Negative12887 - 1334216286.6
predicted l-lactate dehydrogenase, hypothetical protein subunit ykggHHE01_08360Not AvailableNegative13352 - 1399323558.7
predicted l-lactate dehydrogenase, iron-sulfur cluster-binding subunit ykgfHHE01_08370P77536Negative13986 - 1543153921.3
predicted l-lactate dehydrogenase, fe-s oxidoreductase subunit ykgeHHE01_08380Q8ET92Negative15433 - 1616427417.1
inner membrane protein forms channel for type iv secretion of t-dna complex (virb10)HHE01_08390Not AvailableNegative16209 - 1733041487.2
component of conjugal plasmid transfer systemHHE01_08400Not AvailableNegative17327 - 1820532994.2

Displaying genes 31 – 40 of 5261 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

100 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0001035indole-3-pyruvateC11H8NO3Chemical structure of indole-3-pyruvate35656-49-6
Average202.1861Da
Monoisotopic202.0504181Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm00013353-oxo-3-phenylpropanoateC9H7O3Chemical structure of 3-oxo-3-phenylpropanoateNot available
Average163.153Da
Monoisotopic163.0400677Da

Displaying 1–10 of 100 metabolites

Health Effects

Health ConditionRelationReference
Gastric malt lymphomasCausesPMC1828597
Gastric ulcersCausesPMC3964410

Displaying health effects 1 – 2 of 2 in total