Brevibacterium casei

Gram-positiveRodAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Micrococcales

Family

Brevibacteriaceae

Genus

Brevibacterium

Description

Brevibacterium casei is a Gram-positive, rod-shaped bacterium classified as a facultative anaerobe that thrives at mesophilic temperatures, typically around 30-37°C, and is considered a chemoheterotroph. This microorganism is primarily found in various body sites and environments, including the skin, mouth, and intestines of humans and animals, as well as in dairy products, particularly cheeses. As a Gram-positive bacterium, Brevibacterium casei possesses a thick peptidoglycan layer in its cell wall, which gives it structural integrity and enables it to retain the crystal violet dye used in Gram staining. Its rod-like shape, or bacillus form, allows for versatile interactions with its environment. The mesophilic temperature preference indicates its optimal growth range aligns with the temperature of the human body, facilitating its persistence in human-associated ecosystems. Being a facultative anaerobe, B. casei can grow in the presence or absence of oxygen, which allows it to colonize diverse environments where oxygen levels may fluctuate. As a chemoheterotroph, Brevibacterium casei metabolizes organic compounds for energy and carbon, utilizing carbohydrates, amino acids, and fatty acids found in its surroundings. This metabolic flexibility contributes to its role in food fermentation, especially in cheese production, where it helps develop flavor and texture.Brevibacterium casei is also notable for its association with human skin, where it contributes to the characteristic smell of foot odor due to the production of volatile compounds during protein fermentation. Its presence and activities in both food production and human microbiomes highlight its ecological significance and potential applications in biotechnology and health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMicrococcales
FamilyBrevibacteriaceae
GenusBrevibacterium
SpeciesBrevibacterium casei
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Brevibacterium casei
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatanimal sources; Marine; raw milk; surface-ripened cheese
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Brevibacterium casei strain OG2 NODE_316_length_206_cov_1.00662,

Gene Summary

Adenine Count

632528 bp

Thymine Count

629464 bp

Guanine Count

1305414 bp

Cytosine Count

1318255 bp

Genome Length

3885661 bp

Protein-coding Genes

3528 genes

Non-Coding Genes

63 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fad-dependent oxidoreductaseB8X04_00135Not AvailableNegative32357 - 3417767296.7
diguanylate cyclaseB8X04_00140Not AvailablePositive34361 - 3554842476.8
glyoxalaseB8X04_00145Not AvailableNegative35524 - 3601216977.3
arac family transcriptional regulatorB8X04_00150Not AvailableNegative36092 - 3696730859.6
hypothetical proteinB8X04_00155Not AvailableNegative37100 - 3866553826.5
hypothetical proteinB8X04_00160Not AvailableNegative38686 - 4067167897.4
hypothetical proteinB8X04_00165Not AvailableNegative40622 - 4098413214.5
Ncrna_class:srp_rnaNot AvailableNot AvailablePositive41401 - 41496Not Available
hypothetical proteinB8X04_00170Not AvailableNegative40981 - 4205737748.8
cytochrome ubiquinol oxidase subunit iB8X04_00175Not AvailableNegative42054 - 4355354367.3

Displaying genes 31 – 40 of 3591 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0039735Streptococcus anginosusNot availableNot availableNot available

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
BacteremiaCausesPMC7203332

Displaying health effects 1 – 1 of 1 in total