Brevibacterium casei

Gram-positiveRodAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Micrococcales

Family

Brevibacteriaceae

Genus

Brevibacterium

Description

Brevibacterium casei is a Gram-positive, rod-shaped bacterium classified as a facultative anaerobe that thrives at mesophilic temperatures, typically around 30-37°C, and is considered a chemoheterotroph. This microorganism is primarily found in various body sites and environments, including the skin, mouth, and intestines of humans and animals, as well as in dairy products, particularly cheeses. As a Gram-positive bacterium, Brevibacterium casei possesses a thick peptidoglycan layer in its cell wall, which gives it structural integrity and enables it to retain the crystal violet dye used in Gram staining. Its rod-like shape, or bacillus form, allows for versatile interactions with its environment. The mesophilic temperature preference indicates its optimal growth range aligns with the temperature of the human body, facilitating its persistence in human-associated ecosystems. Being a facultative anaerobe, B. casei can grow in the presence or absence of oxygen, which allows it to colonize diverse environments where oxygen levels may fluctuate. As a chemoheterotroph, Brevibacterium casei metabolizes organic compounds for energy and carbon, utilizing carbohydrates, amino acids, and fatty acids found in its surroundings. This metabolic flexibility contributes to its role in food fermentation, especially in cheese production, where it helps develop flavor and texture.Brevibacterium casei is also notable for its association with human skin, where it contributes to the characteristic smell of foot odor due to the production of volatile compounds during protein fermentation. Its presence and activities in both food production and human microbiomes highlight its ecological significance and potential applications in biotechnology and health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMicrococcales
FamilyBrevibacteriaceae
GenusBrevibacterium
SpeciesBrevibacterium casei
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Brevibacterium casei
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatanimal sources; Marine; raw milk; surface-ripened cheese
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Brevibacterium casei strain OG2 NODE_316_length_206_cov_1.00662,

Gene Summary

Adenine Count

632528 bp

Thymine Count

629464 bp

Guanine Count

1305414 bp

Cytosine Count

1318255 bp

Genome Length

3885661 bp

Protein-coding Genes

3528 genes

Non-Coding Genes

63 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter atp-binding proteinB8X04_00085Not AvailableNegative19158 - 1994928613.8
abc transporter permeaseB8X04_00090Not AvailableNegative19953 - 2095134431.8
sugar abc transporter substrate-binding proteinB8X04_00095Not AvailableNegative21032 - 2201533237.8
oligopeptidase bB8X04_00100Not AvailableNegative22279 - 2463985844.7
tricarboxylic transporterB8X04_00105Not AvailablePositive25200 - 2632138536.8
hypothetical proteinB8X04_00110Not AvailablePositive26318 - 2699524071.0
tripartite tricarboxylate transporter tctaB8X04_00115Not AvailablePositive26997 - 2853553446.6
mfs transporterB8X04_00120Not AvailableNegative28620 - 3017353574.7
tetr family transcriptional regulatorB8X04_00125Not AvailablePositive30274 - 3079518945.6
hypothetical proteinB8X04_00130Not AvailablePositive31618 - 3220222315.8

Displaying genes 21 – 30 of 3591 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0039735Streptococcus anginosusNot availableNot availableNot available

Displaying 1–1 of 1 metabolites

Health Effects

Health ConditionRelationReference
BacteremiaCausesPMC7203332

Displaying health effects 1 – 1 of 1 in total