Peptoniphilus indolicus

Gram-positiveCoccusAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Tissierellia

Order

Tissierellales

Family

Peptoniphilaceae

Genus

Peptoniphilus

Description

Peptoniphilus indolicus is a Gram-positive, coccoid-shaped bacterium that thrives in a temperature range of 30-40°C, falling under the mesophilic category. This microbe is a heterotroph, utilizing organic compounds as its energy source, and relies on fermentation as its primary method of energy production. Specifically, it obtains energy by breaking down amino acids, peptides, and other nitrogenous compounds. This microbe is commonly found in various body sites across different species, including the oral cavity, skin, and gastrointestinal tract. Its ability to adapt to these diverse environments is likely facilitated by its robust capacity for fermentative metabolism, which allows it to thrive in the presence of organic matter. P. indolicus is an obligate anaerobe, meaning it requires a lack of oxygen to survive and grow. This is likely an adaptation to its typical environments, where oxygen levels may be limited. In its anaerobic state, the microbe produces a range of metabolic products, including hydrogen gas, carbon dioxide, and various organic compounds. In its natural habitats, P. indolicus plays a significant role in degrading complex organic matter, breaking down proteins and peptides into simpler compounds. This process contributes to the recycling of essential nutrients and the decomposition of organic waste. Furthermore, research has shown that P. indolicus possesses a unique ability to produce indole, a compound with potential antimicrobial properties. This unique characteristic has sparked interest in the microbe's potential applications in the development of novel antibacterial agents. Overall, Peptoniphilus indolicus is a fascinating microbe that has adapted to thrive in a wide range of environments, playing a significant role in the recycling of organic matter and potentially offering new avenues for the development of antimicrobial therapies.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassTissierellia
OrderTissierellales
FamilyPeptoniphilaceae
GenusPeptoniphilus
SpeciesPeptoniphilus indolicus
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCoccus
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Peptoniphilus indolicus
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut biome; sinonasal cavity; stomach; vagina
Biotic relationshipNot Available
Host(s)Bos
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Peptoniphilus indolicus strain NCTC11088 genome assembly, contig:

Gene Summary

Adenine Count

734056 bp

Thymine Count

804033 bp

Guanine Count

321911 bp

Cytosine Count

387968 bp

Genome Length

2247968 bp

Protein-coding Genes

2100 genes

Non-Coding Genes

100 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive81820 - 81832Not Available
Putative radical activating enzymeNCTC11088_00087Not AvailableNegative86667 - 8732325344.6
Qued-like queosine biosynthesis proteinNCTC11088_00088Not AvailableNegative87292 - 8768715438.6
protein-export chaperone secbNCTC11088_00089Not AvailableNegative87996 - 8843016669.8
uncharacterised proteinNCTC11088_00090Not AvailableNegative88431 - 8876313272.4
uncharacterised proteinNCTC11088_00091Not AvailableNegative88764 - 8931521456.0
HolinNCTC11088_00092Not AvailableNegative89504 - 8985713363.7
uncharacterised proteinNCTC11088_00093Not AvailableNegative89976 - 9027511785.2
PeptidaseNCTC11088_00094Not AvailableNegative90242 - 9104830412.7
Xhla hemolysinNCTC11088_00095Not AvailableNegative91058 - 913129980.05

Displaying genes 1 – 10 of 2200 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

7 records
Metabolite IDMetabolite nameStructureCAS number
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da
BASm0014031Butyric acidC4H8O2Chemical structure of Butyric acid107-92-6
Average88.1051Da
Monoisotopic88.0524295Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014039L-Lactic acidC3H6O3Chemical structure of L-Lactic acid79-33-4
Average90.0779Da
Monoisotopic90.031694058Da
BASm0014045Propionic acidC3H6O2Chemical structure of Propionic acid79-09-4
Average74.0785Da
Monoisotopic74.036779436Da
BASm0014079FuranC4H4OChemical structure of Furan110-00-9
Average68.074Da
Monoisotopic68.02621475Da

Displaying 1–7 of 7 metabolites

Health Effects

Health ConditionRelationReference
Bloodstream infectionCausesPMC7815979
BsiCausesPMC7815979

Displaying health effects 1 – 2 of 2 in total