Veillonella parvula

Gram-negativeCocciNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Negativicutes

Order

Veillonellales

Family

Veillonellaceae

Genus

Veillonella

Description

Veillonella parvula is a Gram-negative, cocci-shaped microbe that thrives in mesophilic temperatures, categorized as a Chemoheterotroph, and can be found in various body sites, including the oral cavity, gut, and urogenital tract, of numerous species, including humans, animals, and insects, and is an Obligate Anaerobe. As a Gram-negative microbe, Veillonella parvula has a unique outer membrane containing lipopolysaccharides, which provides protection against environmental stresses. Its cocci shape allows it to maintain a large surface area, facilitating the uptake of nutrients and interaction with other microbes. The mesophilic temperature preference of Veillonella parvula enables it to grow optimally at temperatures between 20-45°C, making it well-suited to inhabit various ecosystems. As a Chemoheterotroph, Veillonella parvula relies on organic compounds for energy and carbon, breaking down lactate, pyruvate, and other substrates to sustain its growth. The presence of Veillonella parvula in diverse body sites and species highlights its adaptability and ability to form symbiotic relationships with its hosts. As an Obligate Anaerobe, Veillonella parvula requires the absence of oxygen to grow, which is reflected in its metabolic pathways and enzymatic systems. Veillonella parvula plays a significant role in the fermentation of lactate, producing propionic acid, acetate, and carbon dioxide, which can influence the pH and composition of its environment, and its ability to metabolize lactate has implications for the development of novel therapeutic strategies, particularly in the treatment of diseases associated with dysbiosis, such as periodontitis and inflammatory bowel disease.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassNegativicutes
OrderVeillonellales
FamilyVeillonellaceae
GenusVeillonella
SpeciesVeillonella parvula
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Veillonella parvula
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Veillonella parvula strain UMB0371 ERR1203608.17957_1_20.14, whole

Gene Summary

Adenine Count

662142 bp

Thymine Count

658738 bp

Guanine Count

427655 bp

Cytosine Count

401603 bp

Genome Length

2150556 bp

Protein-coding Genes

1909 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pur operon repressorCYK26_00045Not AvailablePositive6406 - 722430238.1
bifunctional udp-n-acetylglucosamine diphosphorylase/glucosamine-1-phosphate n-acetyltransferase glmuCYK26_00050Not AvailablePositive7356 - 872948979.5
ribose-phosphate pyrophosphokinaseCYK26_00055Not AvailablePositive8857 - 981034334.8
aminoacyl-trna hydrolaseCYK26_00060Not AvailablePositive9821 - 1039921482.1
arginine 2-monooxygenaseCYK26_00065Not AvailablePositive10457 - 1193854880.2
thymidylate kinaseCYK26_00070Not AvailablePositive11941 - 1262725714.6
hypothetical proteinCYK26_00075Not AvailablePositive12703 - 1374338704.4
stage 0 sporulation family proteinCYK26_00080Not AvailablePositive13744 - 1458931665.7
sam-dependent methyltransferaseCYK26_00085Not AvailablePositive14582 - 1530727720.4
16s rrna (cytidine(1402)-2'-o)-methyltransferaseCYK26_00090Not AvailablePositive15297 - 1614531450.7

Displaying genes 11 – 20 of 757 in total

Metabolites

114 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm00055001-octadecanoyl-sn-glycero-3-phosphateC21H41O7PChemical structure of 1-octadecanoyl-sn-glycero-3-phosphateNot available
Average436.5198Da
Monoisotopic436.2589902Da
BASm0014032Acetic acidC2H4O2Chemical structure of Acetic acid64-19-7
Average60.052Da
Monoisotopic60.021129372Da
BASm0014033AmmoniaH3NChemical structure of Ammonia7664-41-7
Average17.0305Da
Monoisotopic17.026549101Da
BASm0014037Fumaric acidC4H4O4Chemical structure of Fumaric acid110-17-8
Average116.0722Da
Monoisotopic116.010958616Da
BASm0014038Malic acidC4H6O5Chemical structure of Malic acid97-67-6
Average134.0874Da
Monoisotopic134.021523302Da
BASm0014039L-Lactic acidC3H6O3Chemical structure of L-Lactic acid79-33-4
Average90.0779Da
Monoisotopic90.031694058Da
BASm0014041Oleic acidC18H34O2Chemical structure of Oleic acid112-80-1
Average282.4614Da
Monoisotopic282.255880332Da
BASm0014045Propionic acidC3H6O2Chemical structure of Propionic acid79-09-4
Average74.0785Da
Monoisotopic74.036779436Da
BASm0014058Myristic acidC14H28O2Chemical structure of Myristic acid544-63-8
Average228.3709Da
Monoisotopic228.20893014Da

Displaying 1–10 of 114 metabolites

Health Effects

Health ConditionRelationReference
Colorectal carcinogenesisCausesPMC10684188

Displaying health effects 1 – 1 of 1 in total