Capnocytophaga cynodegmi

Gram-negativeMotile

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Flavobacteriia

Order

Flavobacteriales

Family

Flavobacteriaceae

Genus

Capnocytophaga

Description

Capnocytophaga cynodegmi is a gram-negative, spiral-shaped bacterium that thrives in a temperature range of 20-37°C, placing it in the mesophilic temperature preference category. As a heterotroph, it obtains its energy by breaking down complex organic molecules, specifically glucose, rather than producing its own food through photosynthesis or chemosynthesis. This bacterium produces energy through cellular respiration, utilizing the pyruvate fermentation pathway. Capnocytophaga cynodegmi is known to inhabit a wide range of body sites across various species, including the human oral cavity, gastrointestinal tract, and genitourinary tract. It is also detected in animals such as dogs, cats, and horses. This versatility suggests that the bacterium has adapted to survive in a variety of ecological niches. Oxygen preference-wise, Capnocytophaga cynodegmi is a facultative anaerobe, meaning it can thrive in the presence of oxygen but can also survive without it. This adaptability allows it to colonize and remain in environments with varying levels of oxygen availability. Further research has revealed that Capnocytophaga cynodegmi plays a crucial role in the human oral microbiome, contributing to the breakdown of complex carbohydrates and the production of volatile sulfur compounds, which are responsible for the characteristic "bad breath" odor. In addition, studies have linked the bacterium to the development of periodontal diseases, emphasizing the importance of maintaining a balanced oral ecosystem to prevent the overgrowth of opportunistic pathogens. Notably, Capnocytophaga cynodegmi has been recognized as a zoonotic agent, capable of transmitting from animals to humans. While most infections are mild and self-limiting, severe cases can lead to sepsis and even death. Despite its potential pathogenicity, this bacterium serves as a valuable model for understanding the complexities of the human microbiome and the intricate relationships between microorganisms and their hosts.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassFlavobacteriia
OrderFlavobacteriales
FamilyFlavobacteriaceae
GenusCapnocytophaga
SpeciesCapnocytophaga cynodegmi
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityYes
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsNot Available
Optimal temperature37
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Canis lupus familiaris
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Capnocytophaga cynodegmi strain G7591 chromosome, complete genome.

Gene Summary

Adenine Count

856364 bp

Thymine Count

879597 bp

Guanine Count

452579 bp

Cytosine Count

451935 bp

Genome Length

2640475 bp

Protein-coding Genes

2277 genes

Non-Coding Genes

61 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
methylation-associated defense system protein mad7CGC48_RS11530Not AvailablePositive2611407 - 261296660316.6
methylation-associated defense system atp-binding protein mad8CGC48_RS11535Not AvailablePositive2612977 - 2618379206423.0
pp2c family protein-serine/threonine phosphataseCGC48_RS11540Not AvailablePositive2618379 - 261906825906.9
duf4113 domain-containing proteinCGC48_RS11545Not AvailablePositive2619147 - 262027443330.7
is1595 family transposaseCGC48_RS11550Not AvailableNegative2620258 - 26203654401.28
s9 family peptidaseCGC48_RS11555Not AvailableNegative2620757 - 262267072974.5
sdr family nad(p)-dependent oxidoreductaseCGC48_RS11560Not AvailablePositive2622820 - 262350024894.1
duf5723 family proteinCGC48_RS11565Not AvailableNegative2623661 - 262506752674.1
duf456 domain-containing proteinCGC48_RS11570Not AvailableNegative2625431 - 262592517775.0
duf6261 family proteinCGC48_RS11575Not AvailablePositive2626416 - 262709326206.7

Displaying genes 4801 – 4810 of 4824 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

7 records
Metabolite IDMetabolite nameStructureCAS number
BASm0002051D-fructoseC6H12O6Chemical structure of D-fructose57-48-7
Average180.1559Da
Monoisotopic180.0633881Da
BASm0014074LevanC18H32O16Chemical structure of Levan9013-95-0
Average504.4371Da
Monoisotopic504.169034976Da
BASm0014079FuranC4H4OChemical structure of Furan110-00-9
Average68.074Da
Monoisotopic68.02621475Da
BASm0014084GlycogenC24H42O21Chemical structure of Glycogen9005-79-2
Average666.5777Da
Monoisotopic666.221858406Da
BASm0014085AmylopectinC30H52O26Chemical structure of Amylopectin9037-22-3
Average828.7183Da
Monoisotopic828.274681836Da
BASm0014086Amylose(C12H20O11)nC2H6Chemical structure of Amylose9005-82-7Not available
BASm0014087DextrinC18H32O16Chemical structure of Dextrin9004-53-9
Average504.4371Da
Monoisotopic504.169034976Da

Displaying 1–7 of 7 metabolites

Health Effects

Health ConditionRelationReference
Local wound infectionsCausesPMC10269634
SepsisCausesPMC10269634
CellulitisCausesPMC10269634
Skin and soft tissue infectionsCausesPMC11218291
SepsisCausesPMC4780008
MeningitisCausesPMC4780008
EndocarditisCausesPMC4780008
Eye- or wound infectionsCausesPMC4780008
Rare, mild local infectionsCausesPMC6030092

Displaying health effects 1 – 9 of 9 in total