Prevotella disiens

Gram-negativeAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Prevotellaceae

Genus

Prevotella

Description

Prevotella disiens is a gram-negative, rod-shaped microbe that thrives in a broad temperature range, characterized as mesophilic with optimal growth between 25-37°C. As a chemoheterotroph, P. disiens obtains its energy by oxidizing organic compounds, utilizing them as both carbon and energy sources. This process is facilitated through respiratory chain reactions, where the microbe produces ATP from the conversion of glucose and other organic compounds. P. disiens is widely distributed across various body sites, including the oral cavity, gastrointestinal tract, and female genital tract, in diverse species. Its presence is often associated with the human microbiome, playing a role in shaping the immune system and influencing local metabolic processes. As an obligate anaerobe, P. disiens is unable to grow in the presence of oxygen and requires a low-oxygen or anaerobic environment to survive. This is due to the fact that P. disiens lacks the necessary enzymes to handle oxygen, which would otherwise damage the microbe's cell membrane. P. disiens has been implicated in several human diseases, including periodontitis, chronic gingivitis, and pelvic inflammatory disease. However, it is also known to contribute to the breakdown and recycling of organic matter, playing a crucial role in the ecosystem balance. In terms of its genome, P. disiens has been found to possess genes involved in the transportation of sugars and amino acids, as well as the production of enzymes for protein degradation. This adaptation allows P. disiens to thrive in environments where nutrients are limited. Fascinatingly, P. disiens has been shown to produce bioactive compounds, such as prevotellins, which have been linked to antimicrobial and anti-inflammatory activities. These compounds have been found to inhibit the growth of pathogenic bacteria, highlighting the potential of P. disiens as a therapeutic agent in the treatment of certain diseases.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyPrevotellaceae
GenusPrevotella
SpeciesPrevotella disiens
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Prevotella disiens strain NCTC11157 genome assembly, contig:

Gene Summary

Adenine Count

918052 bp

Thymine Count

907462 bp

Guanine Count

610821 bp

Cytosine Count

615017 bp

Genome Length

3051352 bp

Protein-coding Genes

2619 genes

Non-Coding Genes

62 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
succinyl-diaminopimelate desuccinylaseNCTC11157_00910Not AvailablePositive1017291 - 101865250439.3
Tmrna,resume consensus sequence (at 89): attaattggcgaaaacaaNot AvailableNot AvailablePositive1018839 - 1019235Not Available
phenylalanine--trna ligase beta subunitNCTC11157_00912Not AvailablePositive1019623 - 102209192314.3
probable transcriptional regulatory protein cj1172cNCTC11157_00913Not AvailablePositive1022105 - 102283327510.4
predicted methyltransferase (contains tpr repeat)NCTC11157_00914Not AvailableNegative1023046 - 102396335001.5
uncharacterised proteinNCTC11157_00915Not AvailablePositive1024029 - 102429510056.5
acyl-[acyl-carrier-protein]--udp-n- acetylglucosamine o-acyltransferaseNCTC11157_00916Not AvailableNegative1024175 - 102495728290.9
outer membrane protein oprm precursorNCTC11157_00917Not AvailableNegative1024982 - 102636150790.1
efflux pump membrane transporter bepeNCTC11157_00918Not AvailableNegative1026385 - 1029645118971.0
efflux pump periplasmic linker bepfNCTC11157_00919Not AvailableNegative1029667 - 103100446668.8

Displaying genes 911 – 920 of 2681 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

24 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014158N-AcetylhistamineC7H11N3OChemical structure of N-AcetylhistamineNULL
Average153.1817Da
Monoisotopic153.090211989Da
BASm0014202N-ButyrylglycineC6H11NO3Chemical structure of N-ButyrylglycineNULL
Average145.1564Da
Monoisotopic145.073893223Da
BASm0034653Starch, Structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]})C66H112O56Chemical structure of Starch, Structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]})NULL
Average1801.566Da
Monoisotopic1800.591622326Da
BASm0039676Clostridium nexileNot availableNot availableNot available
BASm0040013Bacillus cereus AH187 (F4810/72)Not available13431-24-8Not available
BASm0040450Acinetobacter lwoffiiNot availableNot availableNot available
BASm0040472MarinobacterNot availableNot availableNot available
BASm0040473Lactobacillus reuteri CF48-3ANot availableNot availableNot available
BASm0040476Penicillium echinulatumNot availableNot availableNot available
BASm0040477Lactobacillus gasseri ATCC 33323Not availableNot availableNot available

Displaying 1–10 of 24 metabolites

Health Effects

No health effects information available for this bacterium.