Acinetobacter lwoffii

Gram-negativeRodMotileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Moraxellales

Family

Moraxellaceae

Genus

Acinetobacter

Description

Acinetobacter lwoffii is a Gram-negative, rod-shaped bacterium that thrives in a mesophilic temperature range (optimally at 30-37°C). As a chemoheterotroph, it derives its energy from organic compounds while utilizing oxygen in a facultative anaerobic manner, which allows it to adapt to varying oxygen levels. This bacterium is commonly found in numerous body sites across different species, including humans, where it can inhabit the skin, respiratory tract, and gastrointestinal tract. The Gram-negative nature of Acinetobacter lwoffii is characterized by a thin peptidoglycan layer surrounded by an outer membrane, which contains lipopolysaccharides that play a critical role in its pathogenicity and resistance to antibiotics. The rod shape provides the bacterium with a structural advantage, facilitating its motility and colonization in various environments. This microbe is notably part of the normal flora in humans and is frequently associated with nosocomial infections, particularly in immunocompromised patients. As a facultative anaerobe, Acinetobacter lwoffii can survive in both oxygen-rich and oxygen-poor environments, allowing it to adapt to its host's changing conditions. This versatility enhances its potential to thrive in diverse ecological niches, including environmental sources such as soil and water. Moreover, it exhibits a remarkable ability to acquire antibiotic resistance, making it a serious concern in clinical settings.In addition to its role in human health and disease, Acinetobacter lwoffii is also utilized in bioremediation, demonstrating its capacity to degrade environmental pollutants, thus highlighting its ecological significance beyond its pathogenic potential. Furthermore, ongoing research is investigating its interactions within the human microbiome and potential applications in biotechnology, revealing its multifaceted role in health and environment.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderMoraxellales
FamilyMoraxellaceae
GenusAcinetobacter
SpeciesAcinetobacter lwoffii
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceNot Available
Number of membranesNot Available
Image of Acinetobacter lwoffii
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatoropharynx; skin
Biotic relationshipNot Available
Host(s)Homo sapiens, Metazoa, Equidae
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Acinetobacter lwoffii strain AL_065 plasmid pAL_065-5, complete

Gene Summary

Adenine Count

4619 bp

Thymine Count

4007 bp

Guanine Count

2526 bp

Cytosine Count

2624 bp

Genome Length

13776 bp

Protein-coding Genes

16 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinEVX74_RS16130Not AvailablePositive28827 - 2925215862.0
hypothetical proteinEVX74_RS16135Not AvailablePositive29346 - 2984018582.2
hypothetical proteinEVX74_RS16140Not AvailableNegative29832 - 300929491.19
is4-like element isaba1 family transposaseEVX74_RS16145Not AvailableNegative30385 - 3147543058.5
oxa-134 family carbapenem-hydrolyzing class d beta-lactamase oxa-235EVX74_RS16150Not AvailableNegative31609 - 3243930930.4
is4-like element isaba1 family transposaseEVX74_RS16155Not AvailablePositive32525 - 3361543057.6
hypothetical proteinEVX74_RS16160Not AvailablePositive33727 - 3426320988.3
hypothetical proteinEVX74_RS16165Not AvailableNegative34366 - 3482116701.9
hypothetical proteinEVX74_RS16170Not AvailablePositive35019 - 352317894.23
fic/doc family proteinEVX74_RS16175Not AvailablePositive35301 - 3605929320.0

Displaying genes 51 – 60 of 285 in total

Pathways

1 pathway

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

31 records
Metabolite IDMetabolite nameStructureCAS number
BASm0003448(4,5-dihydro-5-oxofuran-2-yl)-acetateC6H5O4Chemical structure of (4,5-dihydro-5-oxofuran-2-yl)-acetateNot available
Average141.103Da
Monoisotopic141.0193322Da
BASm0003671(S)-muconolactoneC6H5O4Chemical structure of (S)-muconolactoneNot available
Average141.103Da
Monoisotopic141.0193322Da
BASm0014041Oleic acidC18H34O2Chemical structure of Oleic acid112-80-1
Average282.4614Da
Monoisotopic282.255880332Da
BASm0014158N-AcetylhistamineC7H11N3OChemical structure of N-AcetylhistamineNULL
Average153.1817Da
Monoisotopic153.090211989Da
BASm0014202N-ButyrylglycineC6H11NO3Chemical structure of N-ButyrylglycineNULL
Average145.1564Da
Monoisotopic145.073893223Da
BASm0017263NADPC21H29N7O17P3Chemical structure of NADP53-59-8
Average744.4129Da
Monoisotopic744.083277073Da
BASm0018559CDP-DG(16:1(9Z)/18:1(9Z))C46H81N3O15P2Chemical structure of CDP-DG(16:1(9Z)/18:1(9Z))NULL
Average978.108Da
Monoisotopic977.514292916Da
BASm00189042-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)C22H42O9PChemical structure of 2-Acyl-sn-glycero-3-phosphoglycerol (N-C16:1)NULL
Average481.5372Da
Monoisotopic481.256644454Da
BASm00189102-hexadec-9-enoyl-sn-glycerol 3-phosphateC19H37O7PNot availableNULL
Average408.472Da
Monoisotopic408.227690529Da
BASm0019191PE(16:1(9Z)/18:1(9Z))C39H74NO8PChemical structure of PE(16:1(9Z)/18:1(9Z))NULL
Average715.994Da
Monoisotopic715.515205345Da

Displaying 1–10 of 31 metabolites

Health Effects

Health ConditionRelationReference
PeritonitisCausesPMC9615012
ConjunctivitisCausesPMC12680336
Nosocomial infectionsCausesPMC4740782

Displaying health effects 1 – 3 of 3 in total